Optimal Acquisition Time for a Population-based Single-Time-Point Dosimetric Method in Lu-177-PSMA Therapy (EANM 2026) - Sep 29, 2026 - Abstract #EP-1246; "This study aims to determine the optimal acquisition time for the Hänscheid STP method (1), originally developed for Lu-177-DOTATATE, when applied to Lu-177-PSMA therapy. Materials and Twenty-eight patients with metastatic castration-resistant prostate cancer treated with 1-6 cycles of Lu-177-PSMA-617 therapy were retrospectively included, resulting in 96 cycles in total... STP dosimetry using the Hänscheid method is a practical approach for Lu-177-PSMA therapy, although its accuracy is time-dependent and varies across organs, with recommended acquisition time between 24 and 48 h providing acceptable accuracy for most organs, as compared to the 96 h suggested in the original ref (1)."
Clinical • Castration-Resistant Prostate Cancer • Genito-urinary Cancer • Prostate Cancer • Renal Cell Carcinoma • Solid Tumor
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Y. Liu 1; A. Afshar-Oromieh 2; A. Rominger 2; K. Shi 2; G. Mok 1
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