Optimizing acquisition time in 360°ring-shaped CZT SPECT/CT for 177 Lu dosimetry: balancing quantitative accuracy and image quality (EANM 2026) - Sep 29, 2026 - Abstract #EP-1022; "Materials and Total-body SPECT/ CT data from six patients (ten treatment cycles, 6.6-7.7 GBq) undergoing 177Lu-DOTATATE therapy were acquired on a 360° ring-shaped CZT SPECT/CT system at 4, 24, and 48-72 h post-injection, using a standard acquisition time of 28 min... Ring-shaped CZT SPECT/CT enables shortened acquisition for 177Lu dosimetry while maintaining diagnostic acceptability. However, reducing scan time below ~90% of the standard protocol results in dosimetric errors exceeding 20%. These findings define a practical lower limit for acquisition time, supporting protocol acceleration while preserving quantitative accuracy in personalized dosimetry."
Hematological Malignancies
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K. Khamwan 1, 2; W. Handayani 3, 2; D. Hardiansyah 4; M. Chantadisai 5; S. Chokyakorn 1; G. Sgouros 6
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