Occult Plasma Cell Dyscrasia Unmasked After Kidney Transplantation (KIDNEY WEEK 2026) - Oct 2, 2026 - Abstract #TH-PO1049; Pres time: Oct 22, 2026; 10:00 AM - 12:00 PM; Location: Exhibit Hall A, Convention Center; "He underwent living-related kidney transplantation from his sister on 11/5/25 with basiliximab/methylprednisolone induction and tacrolimus, mycophenolate, and prednisone maintenance...He received high-dose dexamethasone followed by daratumumab-based therapy, with immunosuppression reduction...Timing within days of transplantation favored a pre-existing occult disorder rather than de novo post-transplant myeloma, raising concern that native kidney failure attributed to hypertensive nephrosclerosis may have been misclassified. Key lessons are to pursue alternate diagnoses when imaging and immunologic tests are unrevealing, treat light-chain staining as meaningful, and coordinate multidisciplinary care to balance anti-myeloma therapy, immunosuppression, infection risk, and graft preservation."
Cardiovascular • Hematological Disorders • Hematological Malignancies • Infectious Disease • Monoclonal Gammopathy • Multiple Myeloma • Nephrology • Plasmacytoma • Thrombosis • Transplantation
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Syed Haris Mustafa Zaidi; Stefan Charles Hutson; Ravindra Bollu
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