Differential Bioactivation Profiles of Different GS-441524 Prodrugs in Cell and Mouse Models: ProTide Prodrugs with High Cell Permeability and Susceptibility to Cathepsin A Are More Efficient in Delivering Antiviral Active Metabolites to the Lung.

GS-441524 - Copycat Sci

http://www.ncbi.nlm.nih.gov/pubmed/38690769

Christiane E Wobus; Daniel Macedo de Melo Jorge; Hao-Jie Zhu; Jason R Spence; Jiapeng Li; Jingcheng Xiao; Shuxin Sun; Tristan Frum; Weiwen Wang; Xingwu Zhou; Xinwen Wang; Yu-An Hang; Yueting Liu

May 1, 2024