Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress.

Miostat (carbachol) - Alcon

Vesicare (solifenacin) - Astellas

ondansetron - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42100729

Dania Cheaha; Ekkasit Kumarnsit; Nattapon Rotpenpian; Nipaporn Konthapakdee; Panida Chumpong; Sarunnuch Sattayachiti

May 8, 2026