ampicillin / Generic mfg. - LARVOL DELTA

Poultry Proteus mirabilis in selected areas of Hunan, China: Resistance profiles and virulence genes. (PubMed, Poult Sci) - "Resistance was most frequent to Trimethoprim - Sulfamethoxazole (SXT) (81.4%), Ampicillin (AMP) (79.7%), Ciprofloxacin (CIP) (78.0%), and Gentamicin (GEN) (75.4%), followed by Neomycin (NEO) (63.6%) and Chloramphenicol (CHL) (61.0%). Carbapenem resistance was detected in a subset of isolates, including meropenem (MEM) (6.8%) and imipenem (IPM) (11.0%)...In summary, poultry-derived P. mirabilis in Hunan demonstrated high MDR prevalence and frequent carriage of resistance-, virulence-, and environment-related markers. Our findings enrich the epidemiological data on Proteus mirabilis at the farm level and provide scientific guidance for the prevention and control of this disease."

Journal • Infectious Disease

Prevalence and Antimicrobial Resistance Profiles of Bloodstream Pathogens in Feni, Bangladesh. (PubMed, Biomed Res Int) - "Gram-negative isolates exhibited high resistance to ampicillin, amoxyclav, and cefuroxime, whereas amikacin maintained > 70% sensitivity. Gram-positive isolates were largely resistant to third-generation cephalosporins but were very susceptible to gentamicin and ciprofloxacin...Amikacin demonstrated the highest efficacy, supporting its empirical consideration pending susceptibility results. These findings highlight the urgent need for local antibiogram development and strengthened regional resistance surveillance."

Journal • Infectious Disease

Antimicrobial resistance and real-time PCR detection of blaKPC in Klebsiella pneumoniae isolated from wound infections in a tertiary care hospital. (PubMed, Front Antibiot) - "Out of 560 K. pneumoniae isolates, 110 (19.6%) were resistant to meropenem. These resistant isolates also displayed high rates of multidrug resistance, with over 90% resistant to amikacin, ceftazidime, ampicillin, and cefazolin...In conclusion, K. pneumoniae isolates exhibit a concerning rate of carbapenem resistance mediated by the blaKPC gene. Antimicrobial stewardship and molecular surveillance are crucial for the prevention of the spread of carbapenem-resistant K. pneumoniae in clinical settings."

Journal • Infectious Disease • Pneumonia

Fluoroquinolone resistant Escherichia coli in community: molecular analyses of resistance genes, virulence factors, and antimicrobial susceptibility test. (PubMed, Front Microbiol) - "High resistance rates were observed for ampicillin (100%), nalidixic acid (96.6%), ceftriaxone (83.3%), cefepime (81.5%), ciprofloxacin (81.5%), norfloxacin (81.5%), sulfamethoxazole/trimethoprim (75.9%), and nitrofurantoin (71.9%). The frequent coexistence of resistance determinants, virulence factors, and IncF plasmids highlights the adaptive success of these strains and their potential for sustained dissemination. These findings emphasize the need for continuous genomic surveillance, rational antimicrobial use, and region-specific treatment guidelines to mitigate the impact of MDR UPEC in the community."

Journal • Infectious Disease • Nephrology

Antimicrobial Resistance, Virulence and Resistance Genes in Aeromonas From Diseased Fish in China's Major Freshwater Aquaculture Regions. (PubMed, J Fish Dis) - "These isolates exhibited high resistance to ampicillin (98.1%), erythromycin (84.7%) and rifampicin (54.3%), but were susceptible to chloramphenicol, florfenicol and ceftriaxone. Aeromonas isolates in Jiangxi exhibit high genetic diversity, significant virulence potential, andconcerning antibiotic resistance profiles. Of particular concern is A. hydrophila, which poses a high multidrug-resistance risk."

Journal

Antimicrobial resistance of Escherichia coli in Hungarian wild rats and characterization of a CTX-M-1 type ESBL plasmid. (PubMed, Sci Rep) - "The predominant resistance pattern was combined resistance to ampicillin (17.8%) and tetracycline (12%), with plasmid-associated resistance genes blaTEM-1 and tet(A)/tet(B). Phylogenetically, it exhibits a central relationship to human CTX-M E. coli lineages, suggesting a shared genomic background with globally disseminated, human epidemic E. coli lineages. These findings highlight the role of urban brown rats as reservoirs and potential vectors of antimicrobial resistance within the One Health framework and advocate for enhanced surveillance of AMR in urban wildlife to better understand and mitigate the zoonotic transfer of resistance genes."

Journal • Preclinical

Distribution of serotypes, biotype, and antibiotic sensitivity of Haemophilus influenzae in nasopharyngeal carrier children in Lima, Peru. (PubMed, Rev Peru Med Exp Salud Publica) - "Of the isolates, 9/10 were resistant to sulfamethoxazole/trimethoprim, 3/10 to ampicillin and cefuroxime, 2/10 to azithromycin, and no resistance to ceftriaxone was observed. Understanding the carriage status of H. influenzae and local resistance patterns is useful for empirical antibiotic therapy in invasive infections where this bacterium is suspected."

Journal • Infectious Disease • Influenza • Respiratory Diseases

A Ten-Year Study of the Epidemiology and Antimicrobial Resistance of Bacterial Pathogens Associated with Otitis in Crete, Greece. (PubMed, Clin Lab) - "P. aeruginosa, S. aureus, and the Enterobacterales are the predominant bacterial pathogens causing otitis in our area. Regarding Gram-negatives, although resistance rates to commonly-used antibiotics are low, they are increasing over time. Continued surveillance of the prevalence and antimicrobial susceptibility of bacterial pathogens causing otitis is necessary to reassess updated antimicrobial policies and develop appropriate guidelines."

Journal • Infectious Disease • Otorhinolaryngology

Bacteraemia with Meningitis Caused by Listeria Innocua of Unknown Source in an Elderly Patient with Type 2 Diabetes Mellitus: A Case Report and Literature Review. (PubMed, Eur J Case Rep Intern Med) - "Listeria innocua, although considered non-pathogenic in healthy individuals, can cause severe bacteraemia and meningitis in elderly patients with poorly controlled diabetes mellitus.Third-generation cephalosporins are not effective against all Listeria species; empiric treatment in patients >65 years with diabetes mellitus and meningitis must include ampicillin.Recent molecular studies have identified some atypical L. innocua strains carrying virulence genes, challenging the traditional view of the harmlessness of this species."

Journal • Cardiovascular • CNS Disorders • Diabetes • Hypertension • Infectious Disease • Metabolic Disorders • Oncology • Pain • Type 2 Diabetes Mellitus

KLEBSIELLA PNEUMONIAE-INDUCED NEONATAL SEPTIC SHOCK REQUIRING EXTRACORPOREAL MEMBRANE OXYGENATION IN A LATE-TERM INFANT (WRMC 2026) - "Cefepime and Ampicillin were started. This case highlights the importance of recognizing signs of neonatal sepsis for prompt admission. Klebsiella pneumoniae-induced pneumonia can progress rapidly to severe septic shock requiring ECMO. Educating families regarding severity of neonatal sepsis is critical to initiate timely treatment."

Cardiovascular • Hematological Disorders • Hypotension • Infectious Disease • Leukopenia • Metabolic Disorders • Neutropenia • Pneumonia • Pulmonary Arterial Hypertension • Pulmonary Disease • Respiratory Diseases • Septic Shock

Penicillin Allergy Evaluation in Pediatric Patients: Safety of Testing without MDM and the Role of Testing to Ampicillin and Duplicate PrePen® (AAAAI 2026) - "Among 265 patients with negative skin testing who underwent oral challenge to a penicillin (primarily Conclusions Penicillin skin testing using penicillin G, PrePen®, and ampicillin—without MDM testing—demonstrated a NPV of 98%. Inclusion of ampicillin identified an additional 33 patients (26.4%) with positive results. These findings suggest MDM may not be necessary in pediatric penicillin allergy testing protocols and that ampicillin should be considered an essential component of penicillin testing."

Clinical • Allergy • Immunology • Pediatrics

Biochemical and structural analyses of metallo-β-lactamase VIM-28: impact of substitutions at residues 224 and 228 on substrate profile, stability, and zinc affinity. (PubMed, Microbiol Spectr) - "Compared with VIM-26 (R228S), VIM-28 displayed decreased Km (12.5 for VIM-28 vs 513 μM for VIM-26; 9.66 vs 150 μM) and increased kcat/Km(15.3 vs 1.81 μM-1s-1; 28.6 vs 5.89 μM-1s-1) for ampicillin and cephalothin, respectively...The combined L224H/R228S substitutions in VIM-1 increased the catalytic efficiency of the enzyme for ceftazidime by more than one order of magnitude...Notably, the R228S substitution improved zinc binding and thermal stability, supporting enzyme function under zinc-limited host conditions. These findings reveal mechanisms driving MBL diversity and highlight evolutionary strategies sustaining antibiotic resistance."

Journal

Prevalence of methicillin-resistant Staphylococcus aureus and multidrug resistance among food handlers in a hospital food and nutrition unit in Rio de Janeiro, Brazil. (PubMed, Lett Appl Microbiol) - "High resistance rates were observed for penicillin, erythromycin, and ampicillin. Methicillin-resistant S. aureus (MRSA) represented 29% of hand isolates and 47% of nasal isolates, and 26% were multidrug resistant. These findings indicate that food handlers may act as reservoirs and transmission sources of antimicrobial resistance in hospital food service settings, highlighting the need for continuous monitoring, strict hygiene practices, and antimicrobial stewardship programs."

Journal • Infectious Disease

Antimicrobial resistance of bacteria isolated in a resource-limited region: the experience of the North Kivu Provincial Reference Laboratory in the Democratic Republic of the Congo. (PubMed, Front Med (Lausanne)) - "In E. coli, resistance exceeded 60% to ampicillin, amoxicillin/clavulanate, and ciprofloxacin...pneumoniae showed uniform resistance to ampicillin and high resistance to cefuroxime, cefotaxime, gentamicin, and colistin...Recommended actions include participation in WHONET/GLASS program and antibiotic stewardship. In the interim, empiric strategies should favor nitrofurantoin for uncomplicated cystitis, judicious aminoglycoside use where appropriate, early culture, and prompt de-escalation, reserving carbapenems for severe ESBL-risk presentations."

Journal • Infectious Disease • Pneumonia

Molecular basis of ampicillin resistance: combinatorial mechanisms and future strategies. (PubMed, World J Microbiol Biotechnol) - No abstract available

Journal • Review

Hidden carriers: multidrug-resistant bacteria in hedgehogs from a wildlife rescue centre. (PubMed, Front Vet Sci) - "coli isolates were obtained on MacConkey agar (MCA) and MCA with cefotaxime and confirmed by MALDI-TOF MS...More than half of the isolates (37/69; 54%) were multidrug-resistant, with resistance most frequently observed to ampicillin and nalidixic acid...The presence of sequence types and resistance genes commonly associated with human and veterinary infections further supports the relevance of rehabilitated wildlife to the broader epidemiology of AMR. Enhancing biosafety practices and antimicrobial stewardship in wildlife rescue operations is therefore essential to mitigate zoonotic risks within a One Health framework."

Journal • CNS Disorders • Infectious Disease • Psychiatry

Role of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Predicting In-Hospital Mortality in Patients With Diabetic Foot Ulcers Undergoing Amputation: A Retrospective Study. (PubMed, Cureus) - "Elevated postoperative NLR and PLR are independent predictors of in-hospital mortality in DFU patients undergoing MLLA. These readily available biomarkers can assist in early risk stratification and guide postoperative management. The study also provides region-specific data on microbial prevalence and antibiotic susceptibility, supporting more targeted empiric therapy in this high-risk population."

Journal • Retrospective data • Diabetes • Metabolic Disorders

Differences in β-lactamase activity and carbapenem resistance among the Bacillus cereus group. (PubMed, Antimicrob Agents Chemother) - "Although all B. luti isolates lacked carbapenemase genes, they exhibited higher minimum inhibitory concentration (MIC) ranges for ampicillin and meropenem...All B. luti isolates and some B. mosaicus and B. cereus s.s. isolates displayed constitutive enzyme activity for penicillin G, whereas most B. mosaicus and B. cereus s.s. isolates displayed inducible activity, and five displayed silent activity...This is the first study to demonstrate interspecies variability within the B. cereus group regarding the presence of carbapenemase genes and β-lactam resistance profiles. These findings provide crucial insights into β-lactam resistance mechanisms in this bacterial group and provide a foundation for further research."

Journal • Infectious Disease

Preferential Encapsulation of DNA Impurities Derived from pAAV Plasmid Backbone into Recombinant Adeno-Associated Virus Capsids. (PubMed, Hum Gene Ther) - "These samples contained 0.49-3.80% detectable DNA impurities derived from the three plasmids, as estimated by the ampicillin resistance gene (ampR)...Analysis of the terminal sequences of the long reads containing backbone sequences revealed that 92.7-98.4% of them contained Rep-binding elements. These results indicate that the pAAV backbone in linear DNA form was cleaved from pAAV-ZsGreen1 by Rep78/68 nicking at trs in the nucleus, and that the single-stranded DNA was efficiently translocated into the capsids through the encapsulating machinery, similar to the rAAV genome."

Journal • Gene Therapies

Listeriosis - a retrospective study of 5 years on risk factors and clinical outcomes at a tertiary care hospital in Islamabad, Pakistan. (PubMed, Access Microbiol) - "Ampicillin-based regimens were the most frequently used treatments, and all isolates were sensitive to the tested antibiotics...This study highlights how listeriosis poses substantial morbidity and mortality risk, especially in pregnant cases. There is also a critical data gap, emphasizing the need for better diagnostic strategies, timely and targeted interventions, awareness of the clinical team and public health surveillance to reduce the burden of this often-overlooked infection in Pakistan."

Clinical data • Journal • Retrospective data • Cardiovascular • Chronic Kidney Disease • Diabetes • Hypertension • Infectious Disease • Metabolic Disorders • Nephrology • Oncology • Pain • Renal Disease • CRP

Incidence and pattern of antimicrobial resistance of main bacterial isolates from patients with communityacquired urinary tract infections in North of Iraq. (PubMed, Arch Ital Urol Androl) - "Community-acquired UTI pathogens in Sulaimani  showed high resistance to widely used oral antibiotics, while carbapenems and nitrofurantoin remained effective. Higher resistance was especially noted among older adults, men, and patients with diabetes or renal disease. These findings highlight the need for improved empirical therapy and ongoing resistance surveillance."

Journal • Cardiovascular • Diabetes • Hypertension • Infectious Disease • Metabolic Disorders • Nephrology • Renal Disease

Antibacterial capacity interactions between Aristotelia chilensis (Mol.) Stuntz leaf extract and commercial antibiotics. (PubMed, Nat Prod Res) - "Combining the extract with ampicillin or chloramphenicol, the extract reduced the MICs of the antibiotics by up to six-fold. The interaction of maqui leaf extracts with conventional antibiotics was found to significantly enhance antibacterial activity, reducing required antibiotic doses and highlighting their relevance in combating antimicrobial resistance."

Journal • Infectious Disease

Adsorptive elimination of antibiotics from contaminated water utilising customised zirconia: material synthesis, characterisation, and efficiency in tetracycline and ampicillin removal. (PubMed, J Environ Manage) - "Interference assays demonstrated that cations commonly present in surface waters exerted minimal impact on antibiotic uptake, underscoring the sorbent's high selectivity and resistance to competitive ionic effects. Taken together, these findings demonstrate that microparticulate ZrO2 is a promising material for ampicillin and tetracycline removal from water, reducing ecotoxicity and contributing to antimicrobial resistance mitigation."

Journal

Tracking Antimicrobial Resistance in Typhoidal Salmonella, 2020-2024: Output from An Antimicrobial Resistance Surveillance Network in New Delhi, India. (PubMed, Indian J Med Microbiol) - "Susceptibility to traditional first-line agents is improving, and multidrug resistance is low; however, fluoroquinolone resistance remains high. Ongoing AMR surveillance and prudent antibiotic use are essential to sustain treatment efficacy."

Journal • Infectious Disease

Design of Ampicillin Loaded-Electrospun Citric Acid/PVA/Dextran Nanofibers for In Vivo Wound Healing Applications: Synthesis and In Vivo Assessment. (PubMed, Chem Biodivers) - "The obtained results demonstrated that controlled local delivery of AMP through optimized CA-cross-linked PVA/Dex NFs markedly accelerates wound healing. Therefore, the developed AMP-loaded CA/PVA/Dex electrospun nanofibrous mats represent a novel, biocompatible, and effective wound dressing platform with strong potential for clinical wound management."

Journal • Preclinical • Addiction (Opioid and Alcohol)