ACI-19764 / AC Immune - LARVOL DELTA

AC Immune Reports Second Quarter 2025 Financial Results and Provides a Corporate Update (GlobeNewswire) - "Three active immunotherapies for precision prevention of neurodegeneration progressing through Phase 2 clinical development; ACI-7104.056 anti-alpha-synuclein active immunotherapy in Parkinson’s disease produced strong immunogenicity and favorable safety profile in interim results from the ongoing Phase 2 VacSYn...with further data to come in H2 2025; Third Alzheimer’s disease cohort (AD3) in the Phase 2 ABATE trial of anti-Abeta ACI-24.060 to reach 12 months of treatment in December 2025, with interim results expected early 2026....'We also expect to file an IND for ACI-19764 this year.'"

Clinical data • IND • Alzheimer's Disease • Parkinson's Disease

AC Immune Reports Full Year 2024 Financial Results and Provides a Corporate Update (GlobeNewswire) - "ACI-19764 small molecule NLRP3 inhibitor is undergoing in vivo proof of concept with results expected in 2025 anticipated to enable investigational new drug (IND) application. Our Morphomer Tau and Morphomer a-syn small molecule aggregation inhibitors have made steady progress with selection of lead candidates expected in 2025."

Pipeline update • Preclinical • CNS Disorders