albendazole / Generic mfg. - LARVOL DELTA

Potential of Aframomum melegueta and Xylopia aethiopica Against Taenia spp.: Plant-Based Remedies as Novel Anthelmintics. (PubMed, Pharmaceuticals (Basel)) - "Niclosamide and praziquantel have proven to be effective in treating it, but the use of the same drugs can lead to resistance, so alternative drugs need to be explored...Cell viability was further evaluated using propidium iodide (PI) staining, with albendazole (20 mg/mL) as the reference drug... These results underscore the potential of AM and XA extracts and fractions as alternative treatments for helminth infections. Further, in vivo studies are warranted to confirm their safety and therapeutic efficacy."

Journal • Infectious Disease

Nitazoxanide Analogs: Synthesis, In Vitro Giardicidal Activity, and Effects on Giardia lamblia Metabolic Gene Expression. (PubMed, Int J Mol Sci) - "The standard treatment for this parasitic infection involves the administration of nitroimidazoles, albendazoles, and nitrothiazoles. Furthermore, FLP-2, FLP-6, and FLP-8 demonstrated efficacy against drug-resistant strains. These findings suggest that FLP-2, FLP-6, and FLP-8 are promising candidates for the treatment of giardiasis, as they effectively reduce parasite viability, modify gene expression, and exhibit activity against drug-resistant G. lamblia strains."

Journal • Preclinical • Infectious Disease • GAPDH

Small-Lungworm (Protostrongylidae) Infections in Relation to Meat Sheep Breeds, Mediterranean Climates, and Anthelmintic Regimens. (PubMed, Vet Sci) - "The anthelmintic regimen (ivermectin, levamisole, and albendazole) directly targets gastrointestinal nematodes and indirectly protostrongylids. The use of effective drugs targeting protostrongylids at key moments may provide more effective control."

Journal • Infectious Disease

A Rare Case Report of Pancreatic Hydatid Cyst From Syria: A Diagnostic and Therapeutic Challenge. (PubMed, Clin Med Insights Case Rep) - "Antiparasitic drugs, such as albendazole or mebendazole, are administered to kill the parasite. This instance highlights the significance it is to take hydatid disease into consideration when making a differential diagnosis for pancreatic cystic lesions, particularly in people from endemic regions. For the optimal possible patient outcomes and avoiding of complications, early diagnosis and effective treatment are important."

Journal • Infectious Disease

Study on the effect of GCY-12 gene on albendazole sensitivity of Haemonchus contortus by RNA interference. (PubMed, Front Vet Sci) - "The results showed that the gene expression level decreased significantly after GCY-12 interference, and the sensitivity of H. contortus to albendazole increased. This study highlights the potential role of GCY-12 in modulating albendazole resistance in H. contortus, offering new insights for developing effective therapeutic approaches."

Journal

Serendipity in Emergency Diagnostics: Near Miss of a Loa loa Case in a Swiss Hospital. (PubMed, Clin Case Rep) - "During an influenza epidemic, PCR confirmed Influenza A. The patient was reassured and prescribed ibuprofen and paracetamol. The patient was referred for specialist consultation. Treatment with albendazole was initiated, leading to gradual improvement."

Journal • Cough • Fatigue • Infectious Disease • Influenza • Malaria • Pulmonary Disease • Respiratory Diseases • CRP

From Farm to Operating Table: Pulmonary Hydatidosis in a Sheep Herder (ATS 2025) - "He was diagnosed with cystic pulmonary hydatidosis and started on albendazole and praziquantel. Case studies associate untreated pulmonary hydatid disease with acute and chronic pulmonary embolism. This case illustrates the consequences of late detection of Echincoccus, including extended hospitalization, multiple thoracic surgeries and downstream complications."

Cachexia • Cardiovascular • Cough • Eosinophilia • Hematological Disorders • Hepatology • Infectious Disease • Pain • Pruritus • Pulmonary Disease • Pulmonary Embolism • Respiratory Diseases

A Rare Case of Disseminated Strongyloidiasis Presenting as Polymicrobial Sepsis in a Patient With Lupus: A Diagnostic Conundrum (ATS 2025) - "He was started on systemic ivermectin and albendazole...Given the delay in diagnosis and associated higher mortality rates, screening for Strongyloides infection using stool studies before initiating immunosuppressive therapy should be considered, especially for people in endemic areas. This can help prevent fatal complications through early case detection."

Clinical • Gastroenterology • Gastrointestinal Disorder • Hematological Disorders • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Pulmonary Disease • Respiratory Diseases • Septic Shock

Eosinophilic Fasciitis With Pulmonary Granulomas: A Mimicker of Sarcoidosis (ATS 2025) - "She subsequently developed associated persistent, peripheral eosinophilia, concerning for parasitic infection, and was diagnosed and treated for Strongyloides infection with ivermectin and albendazole...She was treated with low-dose prednisone, as she could not tolerate higher doses, and Cellcept...Raynaud's phenomenon, dysphagia, positive ANA, and systemic sclerosis-specific autoantibodies are not generally present in EF. This case highlights the challenge of differentiating EF from other disorders, such as SS and Sarcoidosis, as it may impact therapeutic management."

Cardiovascular • Eosinophilia • Eosinophilic Granulomatosis With Polyangiitis • Fibrosis • Gastrointestinal Disorder • Hematological Malignancies • Herpes Zoster • Hypereosinophilic Syndrome • Immunology • Infectious Disease • Langerhans Cell Histiocytosis • Monoclonal Gammopathy • Musculoskeletal Pain • Novel Coronavirus Disease • Oncology • Pain • Rare Diseases • Rheumatology • Sarcoidosis • Scleroderma • Systemic Sclerosis • Varicella Zoster • Vasculitis

From Liver to Lungs: A Rare Case of Hepatopulmonary Fistula Following Hepatic Abscess Rupture (ATS 2025) - "Broad-spectrum antibiotics (metronidazole, ceftriaxone, later escalated to piperacillin-tazobactam) and albendazole were initiated...Aspirate cultures grew gram-negative rods and gram-positive cocci, leading to vancomycin and meropenem...Despite maximal vasopressor (norepinephrine, vasopressin, epinephrine) and inotropic support (dobutamine), she experienced refractory hypoxemia and worsening multiorgan failure...The CT findings of gas-filled hepatic abscesses suggested anaerobic infection, and the absence of travel history reduced suspicion of a parasitic cause, guiding broad-spectrum antibiotic coverage for likely polymicrobial infection. This case ultimately underscores the importance of early recognition, comprehensive imaging, and balancing aggressive and conservative management, with a need for standardized guidelines in HPF care for critically ill patients."

Clinical • Cardiovascular • Cough • Endocrine Disorders • Fatigue • Hepatology • Hypertension • Infectious Disease • Musculoskeletal Pain • Oncology • Pain • Respiratory Diseases • Septic Shock

How Bronchoscopy Helped Uncover Acute Eosinophilic Pneumonia Behind a Mask of Community-acquired Pneumonia (ATS 2025) - "Patient was admitted and treated for community-acquired pneumonia with ceftriaxone and azithromycin...Patient ultimately improved on IV methylprednisolone and oral prednisone of varying doses adjusted according to oxygen requirements, respiratory status, eosinophil count, and CRP. He was also treated with albendazole for Strongyloides IgG positive status...Significant peripheral eosinophilia is often absent, making it harder to assess improvement and guide steroid dosing. Most patients improve with steroid treatment, with doses adjusted according to clinical picture."

Anorexia • Cough • Eosinophilia • Eosinophilic Granulomatosis With Polyangiitis • Immunology • Infectious Disease • Interstitial Lung Disease • Langerhans Cell Histiocytosis • Pneumonia • Rare Diseases • Respiratory Diseases • Vasculitis

Uncommon Presentation of Pulmonary Echinococcosis With a Bacterial Superinfection in a Non-endemic Region (ATS 2025) - "The patient was discharged on a course of amoxicillin-clavulanic acid with close follow-up. Upon follow-up, echinococcal serology was positive, eosinophilia had resolved, and albendazole therapy was initiated for suspected echinococcal cyst...Peripheral eosinophilia can be a helpful diagnostic tool when evaluating for cyst spillage, as it is not typically expected in uncomplicated cysts nor pyogenic abscesses. This case highlights the importance of considering rare parasitic infections, even in non-endemic regions, as increased immigration can lead to increased prevalence of tropical diseases, even when initial diagnoses seem straightforward."

Cough • Eosinophilia • Hepatology • Infectious Disease • Oncology • Pain • Rare Diseases • Respiratory Diseases • Tuberculosis

The Sleeping Beauty: Pulmonary Echinococcosis Manifesting After Two Decades of Dormancy (ATS 2025) - "Postoperatively, she was treated with albendazole for 12 months, due to the risk of recurrence or dissemination...This case underscores the complexity of diagnosing pulmonary echinococcosis in non-endemic areas, especially with negative serology. Echinococcal serological tests have limited sensitivity, especially in patients with isolated pulmonary involvement. The prolonged latency period in this patient suggests that E. granulosus can remain dormant for extended periods, only manifesting clinically decades after last exposure."

Infectious Disease • Septic Shock

The Importance of a Correct Timing in Management Pulmonary Echinococcosis (ATS 2025) - "With such suspicion, therapy with albendazole was started...It's essential for clinicians to consult an expert center for a comprehensive assessment, which should cover differential diagnoses, treatment options, and a long-term management strategy. Early diagnosis followed by timely surgical removal of cysts is crucial to prevent complications"

Immunology • Infectious Disease • Metabolic Disorders • Pulmonary Disease • Respiratory Diseases • Tuberculosis

A Single Pulmonary Cyst in a Child: Keep Echinococcosis Hydatid Disease in Mind as a Differential Diagnosis (ATS 2025) - "Because of the clinical worsening and the high suspicion for lung hydatid cyst, patient was treated empirically with Albendazole for one month with no improvement... Pulmonary hydatid disease can present as a single lung cyst and should be considered in the differential diagnosis particularly in endemic areas. Physicians should not rely on serology alone for diagnosis as it can be falsely negative. Surgical intervention is often required."

Clinical • Cough • Infectious Disease • Pain • Pediatrics • Respiratory Diseases

Emergent of Multiple Intracranial Nodules Amidst Treatment for Pott's Disease: A Diagnostic Challenge (ATS 2025) - "Patient was managed clinically as neurocysticercosis versus schistosomiasis, and was discharged stable with Dexamethasone, Albendazole and Praziquantel...The patient was treated with Levofloxacin, Pyrazinamide, Pyridoxine, Cycloserine, Kanamycin and Prothionamide due to multi-drug resistance patterns...Conclusion Despite ongoing treatment for tuberculosis, it is imperative to rule out tuberculous meningitis in cases when patients present with meningeal irritation, severe headache, seizures and focal neurologic deficits. Lumbar tap is imperative as radiologic findings are nonspecific, and may mimic other entities such as neurocysticercosis, schistosomiasis, toxoplasmosis, malignancy, or abscesses."

Back Pain • CNS Disorders • Epilepsy • Infectious Disease • Influenza • Musculoskeletal Pain • Oncology • Pain • Respiratory Diseases • Tuberculosis

BEYOND THE LIVER: EXPLORING EXTRAHEPATIC CYSTIC ECHINOCOCCOSIS IN CHILDREN (ESPID 2025) - "Due to the progressive enlargement of the renal cyst, the lesion was surgically enucleated and albendazole was administered pre- and postoperatively for four weeks...Learning Points/Discussion Given the increasing migratory flows in Europe, these cases highlight the importance of taking a detailed patient history, including prior living environments and contact with animals, while remaining mindful of local epidemiology. Surgery remains the cornerstone of treatment; however, medical therapy plays an increasingly important role as an adjuvant to reduce the risk of recurrence."

Clinical • Infectious Disease

A CHALLENGING CASE OF HEPATIC AND PULMONARY ECHINOCOCCOSIS IN A PEDIATRIC PATIENT: DIAGNOSIS, TREATMENT, AND SURGICAL INTERVENTION (ESPID 2025) - "The girl was treated with albendazole for three months at an appropriate dosage... This case highlights the need for careful follow-up and timely intervention in cases of multi-organ echinococcosis. Despite initial treatment, surgical intervention was essential due to lesion progression and persistent symptoms. The combination of medical and surgical management is crucial for preventing complications and ensuring favorable outcomes."

Clinical • Infectious Disease • Septic Shock

SEVERE MULTIFOCAL TOXOCARIASIS INVOLVING THE EYE AND BRAIN IN A CHILD (ESPID 2025) - "Treatment with albendazole (15 mg/kg/day in three 14-day courses, once per month) was initiated, leading to resolution of left eye inflammation...Learning Points/Discussion Although human toxocariasis is a common self-limiting parasitic zoonosis, central nervous system and ocular involvement require aggressive pharmacological treatment due to their severe and potentially long-term consequences. This case underscores the importance of early recognition and multidisciplinary management to prevent complications."

Clinical • Infectious Disease

SEVERE AND PERSISTENT EOSINOPHILIA: A COMPLEX CASE OF REFRACTORY TOXOCARIASIS (ESPID 2025) - "The patient was initially treated with albendazole (400 mg twice daily for 5 days) and prednisone (1 mg/kg/day)...Tapering the prednisone resulted in recurring eosinophilia, prompting off-label use of ivermectin and hydrocortisone for tertiary adrenal insufficiency...It is crucial to rule out other potential causes when patients fail to respond, as this can help refine the diagnosis and guide appropriate management. Large and well-defined clinical studies regarding the optimal treatment duration for toxocariasis are needed, especially in children."

Clinical • Infectious Disease

A RARE CASE OF DISSEMINATED HYDATID DISEASE IN A PEDIATRIC REFUGEE: DIAGNOSTIC AND MANAGEMENT CHALLENGES ACROSS BORDERS (ESPID 2025) - "Albendazole therapy was initiated immediately, with perioperative praziquantel, anti-epileptics, and corticosteroids added. Clinicians in non-endemic areas must remain vigilant to tropical infections due to increasing international travel. Early multidisciplinary intervention is essential for favorable outcomes."

Clinical • Infectious Disease • Septic Shock

CUTANEOUS LARVA MIGRANS: THE FORGOTTEN ZOONOSIS IN DEVELOPED COUNTRIES (ESPID 2025) - "The clinical presentation was a pruritic skin lesion forming a serpiginous erythema on their feet in two of them and the third in his hand.One of them was initially misdiagnosed as a fungal infection.Treatment with albendazole or ivermectine and antihistamines resulted in complete resolution of symptoms...Raising awareness among physicians, conducting observational studies, and developing pediatric-treatment guidelines are essential steps to address this public health concern. Prevention through promoting hygiene and the use of appropriate footwear is another key point to stop the observed increase in incidence."

Infectious Disease

NEUROCYSTICERCOSIS IN ADOLESCENTS: A RARE CAUSE OF SEIZURES (ESPID 2025) - "The patient responded well to a 10-day course of oral albendazole, corticosteroids, and levetiracetam, experiencing no further seizures...Brain MRI findings provided strong evidence of NCC, demonstrating the pathognomic presence of scolex by a ring enhancing lesion with surrounding edema - hallmarks of a viable or degenerating Taenia solium cyst. The patient's rural exposure likely contributed to his infection."

Infectious Disease

TOXOCARIASIS IN AN IMMUNOCOMPETENT PEDIATRIC PATIENT- A CASE REPORT (ESPID 2025) - "Due to a high suspicion of parasitic infection, blood serology for Toxoplasma gondii, Toxocara canis, Trichinella spiralis and Echinococcus granulosus were collected and antiparasitic treatment was initiated with Albendazole for 5 days. The patient also received Prednisone...Learning Points/Discussion This case highlights the importance of considering zoonotic parasitic infections in pediatric patients presenting with marked eosinophilia. Early recognition and treatment are crucial to prevent complications such as vision loss and neurological disorders, ensuring better health outcomes."

Case report • Clinical • Infectious Disease • Septic Shock • CRP

CUTANEOUS LARVA MIGRANS IN THREE CHILDREN FROM SUBURBAN DAKAR: A CASE SERIES (ESPID 2025) - "All cases achieved complete recovery with oral albendazole treatment...Examination revealed an erythematous and serpiginous lesion on the back (Figure 3). Learning Points/Discussion These cases underscore the need for increased awareness of CLM among healthcare providers and preventive measures in resource-limited settings, where children are particularly vulnerable to this neglected tropical disease."

Clinical • Infectious Disease