albendazole / Generic mfg. - LARVOL DELTA

Amiodarone promoted autophagy and enhanced tissue repair, outperforming albendazole in treating the muscular phase of experimental trichinellosis spiralis. (PubMed, J Mol Histol) - "Our results revealed, for the first time, the exceptional potential of AMD as an autophagy modulator and regenerative supporter in treating trichinellosis. Thus, further investigations for the role of autophagy inducers as therapeutic options against other parasitic infections are recommended."

Journal • Infectious Disease • Inflammation • MAP1LC3B

Challenge to Eliminate Parasite Palatal Infestation in a Deaf-Mute Geriatric Patient. (PubMed, Case Rep Dent) - "Surgical tooth extraction and maggot removal were both performed under general anaesthesia. The patient was also given albendazole to eliminate any remaining larvae."

Journal • Anesthesia • Dental Disorders • Geriatric Disorders • Pain • Periodontitis

Enterobius vermicularis as an Intraoperative Surprise in a Child With Suspected Appendicitis and Normal Laboratory Findings. (PubMed, Cureus) - "The patient recovered uneventfully and received antihelminthic therapy with albendazole. This case highlights the importance of considering parasitic infections in the differential diagnosis of appendicitis, particularly in pediatric patients with atypical presentations. It also emphasizes the diagnostic value of intraoperative findings and histopathology in guiding postoperative management."

Journal • Gastroenterology • Gastrointestinal Disorder • Infectious Disease • Inflammation • Pain • Pediatrics • CRP

Identification of natural products and synthetic analogs which inhibit microsporidia spores and prevent infection. (PubMed, J Invertebr Pathol) - "Current treatments, such as the drugs albendazole and fumagillin, are limited in efficacy...Additionally, five of the identified compounds were effective against Pancytospora epiphaga, a species related to human-infecting microsporidia. Together this work identifies and characterizes compounds that inhibit microsporidia infection."

Journal • Infectious Disease

Effects of Abrus cantoniensis capsule on gut microbiota and intestinal barrier in mice infected with alveolar echinococcosis. (PubMed, Phytomedicine) - "ACC can enrich Ligilactobacillus to modulate the gut microbiota, and protect intestinal mucosal integrity, thereby reducing the translocation of endotoxins to the liver and alleviating liver fibrosis eventually."

Journal • Preclinical • Fibrosis • Immunology • Infectious Disease • Liver Cirrhosis • Oncology • IL6 • MUC2 • OCLN • TJP1 • TNFA

In silico screening of flavonoid-based inhibitors targeting UDP-galactopyranose mutase of Brugia malayi for lymphatic filariasis drug design. (PubMed, Comput Biol Med) - "Drugs such as albendazole, ivermectin, and diethylcarbamazine are used to treat LF; however, they mainly act against the microfilarial stage and have limited effect on the adult worms...Molecular docking and binding free energy calculations identified ligand5 as exhibiting strong and stable binding comparable to the control. Complementary DFT analysis and ADMET predictions further highlighted ligand 5's favourable chemical reactivity and pharmacokinetic properties, indicating it as a promising candidate for further experimental validation in the development of novel therapeutics against all stages of LF infection."

Journal • Infectious Disease

Isolated intramuscular cysticercosis of the abdominal wall. (PubMed, J R Coll Physicians Edinb) - No abstract available

Journal

Evaluation of the use of vinpocetine in microsporidia infections. (PubMed, Diagn Microbiol Infect Dis) - "Except for the control groups, the other groups were infected with E. intestinalis spores after the application of cyclophosphamide. As a result, although the effect of vinpocetine on E. intestinalis virulence needs to be supported by larger studies, this study showed that vinpocetine alone has a positive effect on tissue damage. It has also been observed that it does not negatively alter the effectiveness of albendazole when used as a dietary supplement."

Journal • CNS Disorders • Infectious Disease

Species Diversity, Benzimidazole Resistance, and Phytochemical Synergy in Gastrointestinal Nematode Nemabiomes from Sheep Farms in Portugal. (PubMed, Exp Parasitol) - "This study assessed ovicidal activity of eight natural aromatic phytochemicals and interactions with synthetic benzimidazoles (BZs: albendazole [ABZ], thiabendazole [TBZ]) against nemabiome eggs of 14 BZ-resistant sheep farms across Trás-os-Montes, Beira Interior, Estremadura, and Alentejo regions of Portugal...Synergistic mechanisms involving aromatic phytochemical-induced eggshell damage, complementing BZ β-tubulin disruption, are discussed. BZ-phytochemical combinations offer a promising strategy for sustainable GIN control, warranting in vivo validation."

Journal

In Vitro Efficacy of Albendazole Against the Metacestode Parvitaenia cochlearii (Cestoda), a Parasite of the Pacific Fat Sleeper (Dormitator latifrons). (PubMed, J Fish Dis) - "The LC50 value decreased over time, with 618.91 mg/L at 10 min and 260.32 mg/L at 15 min, indicating a cumulative effect of ABZ on metacestode tissues. In conclusion, ABZ is an effective treatment against cestode infestations, and further evaluation under experimental and commercial scales is recommended to establish control protocols in aquaculture systems."

Journal • Preclinical

Central Nervous System Toxocariasis: A Rare Cause of Eosinophilic Vasculitis and Pulmonary Involvement (ACAAI 2025) - "However, persistent eosinophilia despite three weeks of therapy with albendazole, along with positive Toxocara serology, led to a revised diagnosis of CNS toxocariasis...It illustrates the diagnostic complexity of parasitic infections affecting the CNS. Although rare, CNS toxocariasis should be considered in the appropriate clinical context, particularly in patients with unexplained eosinophilia."

Eosinophilia • Hematological Disorders • Infectious Disease • Vasculitis

Hypereosinophilic Syndrome or Toxocariasis: Importance of a Thorough Workup Beyond Stool Testing (ACAAI 2025) - "At this time she was being considered for treatment with mepolizumab for a working diagnosis of Hypereosinophilic Syndrome (HES). Further testing revealed a positive Toxocara Immunoglobulin G. The patient was treated with albendazole, leading to normalization of eosinophil counts...Discussion This case highlights the importance of a thorough workup for hypereosinophilia. It also highlights the potential limitations of O&P stool testing in detecting parasitic infections, especially when considering diagnosing and treating for possible HES."

Allergic Rhinitis • Cardiovascular • Eosinophilia • Human Immunodeficiency Virus • Hypereosinophilic Syndrome • Hypertension • Immunology • Infectious Disease

Comparative analysis of lncRNA-mRNA networks in albendazole-resistant Haemonchus contortus. (PubMed, Genes Genomics) - No abstract available

Journal

A rare case of intravesical and urethral cystic Echinococcosis with multi-organ involvement from Türkiye. (PubMed, J Infect Dev Ctries) - "By a multidisciplinary approach, the 82-year-old patient was diagnosed with Cystic echinococcosis, with a rare and multi-organ involvement, given the high risk of infection due to the environmental contamination in this country."

Journal • Infectious Disease • Nephrology

Abomasal Nematodes of Goat and In Vitro Evaluation of Anthelmintic Resistance in Arba Minch Zuria District, South Ethiopia. (PubMed, J Parasitol Res) - "The minimum concentration of albendazole that inhibits 50% of egg hatching and embryonation (IC50) was 0.0096 μg/μL...The higher IC50 value for ivermectin suggests a risk of ivermectin resistance in the study area. Therefore, caprine haemonchosis, teladorsagiosis, and trichostrongylosis should be considered during clinical procedures, and combining anthelmintic treatments, creating farmer awareness, and rotating anthelmintic drugs can help reduce the risk of ivermectin resistance."

Journal • Preclinical • Infectious Disease

Rare complex recurrent cystic echinococcosis with multi-organ involvement after inadequate postoperative therapy: a case report. (PubMed, Front Med (Lausanne)) - "He had undergone hepatic CE cystectomy 5 years earlier but did not receive regular albendazole therapy or follow-up...Management of multi-organ recurrent CE requires standardized surgery, multidisciplinary collaboration, prolonged antiparasitic therapy, and strict follow-up. Ensuring patient adherence and providing health education are critical for improving long-term outcomes."

Journal • Critical care • Pain

Hydatid Cyst in the Right Ventricle leading to Tricuspid stenosis and Heart Failure– A Case Report (AHA 2025) - "After 2 weeks of albendazole therapy (400 mg), emergency cardiac surgery was performed...Premedication with midazolam (0.05 mg/kg IV) was administered. General anesthesia was induced with fentanyl (50 µg/kg), thiopental (5 mg/kg), and vecuronium (0.1 mg/kg) for intubation. Anesthesia was maintained with fentanyl (5 µg/kg) and isoflurane...Cardiac hydatid cysts in the right ventricle are exceptionally rare but can be life-threatening. Cardiac involvement is rare as larvae are usually filtered by the liver and lungs; however, some may bypass these organs. The left ventricle is most commonly involved (50%), followed by the right ventricle (20%), interventricular septum (13%), left atrium (9%), right atrium (6%), and interatrial septum (2%)."

Case report • Clinical • Anesthesia • Cardiovascular • Congestive Heart Failure • Heart Failure • Infectious Disease • Pulmonary Disease

Endoscopic management of intraventricular and subarachnoid neurocysticercosis: technical workflow and clinical outcome. (PubMed, Neurosurg Focus) - "Neuroendoscopic surgery offers a safe and effective treatment for IVSN when combined with advanced imaging and structured medical therapy. The integration of 3D SPACE MRI and standardized endoscopic protocols facilitates accurate diagnosis, complete cyst removal, and long-term disease control with low complication and recurrence rates."

Clinical data • Journal • Retrospective data • CNS Disorders • Infectious Disease • Ventriculomegaly

Unmasking the Cause: A Rare Case of Idiopathic Hypereosinophilic Syndrome in a Young Male Presenting with Symptoms of Gastroenteritis (ACG 2025) - "Systemic corticosteroids (prednisone 20 mg TID) were then initiated, resulting in rapid clinical and laboratory improvement: WBC decreased to 12.43 × 10³/μL and AEC to 2.61 × 10³/μL...Albendazole has been effective in treating parasitic causes of eosinophilia, but our patient failed to respond until corticosteroids were initiated...Overall, this case highlights IHES as a rare but important differential diagnosis in patients presenting with GI symptoms and marked eosinophilia. Figure: Figure 1: CT abdomen and pelvis showing nonspecific fluid in pelvis."

Clinical • Cardiovascular • Eosinophilia • Gastroenterology • Gastrointestinal Disorder • Hypereosinophilic Syndrome • Immunology • Rare Diseases

Unmasking the Biliary Trap: Diagnostic and Therapeutic Challenges of Cysto-Biliary Communication in Hepatic Hydatid Disease (ACG 2025) - "Albendazole was initiated preoperatively...C. Histopathology - High power: Highlights crescent-shaped, eosinophilic, chitinous hooks of E. granulosus protoscolices arranged in a diagnostic double row."

Anorexia • Cardiovascular • CNS Disorders • Diabetes • Fibrosis • Hematological Disorders • Hypertension • Infectious Disease • Metabolic Disorders

Trichuris Causing Severe Iron Deficiency Anemia in an Adult in a Non-Endemic Area (ACG 2025) - "She completed albendazole therapy but was unable to access ivermectin due to insurance limitations...TDS in adults is rare with the majority having no to minimal non specific abdominal symptoms such as abdominal pain, diarrhea, occult bleeding, and IDA is usually the reason for endoscopic evaluation which shows large parasite infestation confirming the diagnosis. A broader differential, cultural competence, and attention to healthcare access can guide appropriate workup and management.Figure: Colonoscopy showing internal hemorrhoids, a lipoma, and parasite-Trichuris"

Clinical • Anemia • Cardiovascular • CNS Disorders • Diabetes • Endocrine Disorders • Eosinophilia • Gastroenterology • Gastroesophageal Reflux Disease • Gastrointestinal Disorder • Hematological Disorders • Hypertension • Infectious Disease • Mental Retardation • Metabolic Disorders

The Hidden Culprit: Abdominal Pain Secondary to Parasitic Infection (ACG 2025) - "The patient was treated with albendazole 400mg PO daily for 3 days...A high index of suspicion for parasitic infections in the appropriate clinical context is essential to ensure timely diagnosis and management.Figure: Figure 1. Colonoscopy images of cylindrical, off-white worms at cecum."

Anemia • Crohn's disease • Eosinophilia • Gastroenterology • Gastrointestinal Disorder • Hematological Disorders • Immunology • Infectious Disease • Inflammatory Bowel Disease • Pain • Peptic Ulcer • Pruritus

Schistosomiasis or Ulcerative Colitis? Unraveling the Overlap Between Parasitic Infection and IBD (ACG 2025) - "He was started on mesalamine and prednisone...Symptom improvement following praziquantel and albendazole may reflect parasite clearance, but concurrent steroid use makes it unclear whether recovery was due to anti-parasitic therapy, immunosuppression, or both...Endoscopic image of the rectum showing continuous moderate inflammation consistent with ulcerative colitis, with loss of vascular pattern, erythema, friability, and superficial ulcerations (Mayo 2).Figure: Figure 2. Left colon biopsy: Colonic mucosa with increased lamina propria eosinophils, eosinophilic microabscess, and parasite ova/larva."

Dermatology • Gastroenterology • Gastrointestinal Disorder • Immunology • Infectious Disease • Inflammation • Inflammatory Bowel Disease • Ulcerative Colitis

A Squirmy Surprise: Enterobiasis vermicularis Treatment in Pregnancy (ACG 2025) - "Pyrantel pamoate is preferred to albendazole and mebendazole due to poor systemic absorption limiting fetal exposure. In order to prevent reinfection, hygienic measures should be implemented to include washing bedsheets, fingernail clipping and, frequent handwashing. Due to the endemic nature of pinworms and their potential complications, physicians need greater awareness and understanding on treatment in pregnancy.Figure: Pinworm in rectumFigure: Pinworm in sigmoid colon"

Gastroenterology • Gastrointestinal Disorder • Infectious Disease • Pruritus

Chronic Strongyloidiasis Presenting With Severe Sepsis and Hemorrhagic Enteritis: A Case Report (ACG 2025) - "Treatment with ivermectin was started for 1 month and albendazole for 7 days for severe disease...Thus a high level of clinical suspicion is necessary for prompt diagnosis and treatment of these cases to reduce mortality rates.Figure: Low power gastric mucosa with parasites. Figure: Duodenal image of duodenitis."

Case report • Clinical • Anemia • Cardiovascular • Chronic Kidney Disease • Dermatology • Diabetes • Eosinophilia • Gastrointestinal Disorder • Hematological Disorders • Hypotension • Infectious Disease • Metabolic Disorders • Nephrology • Pneumonia • Pulmonary Arterial Hypertension • Pulmonary Disease • Renal Disease • Respiratory Diseases • Septic Shock