APD597 / Pfizer - LARVOL DELTA

Structure of human GPR119-G complex binding APD597 and characterization of GPR119 binding agonists. (PubMed, Front Pharmacol) - "The interaction between APD597 derivatives and synthetic agonists with GPR119 was analyzed by molecular docking technique, and the necessary structural framework was obtained. The above conclusions can provide structural and theoretical basis for the development of therapeutic drugs for type 2 diabetes mellitus."

Journal • Diabetes • Metabolic Disorders • Type 2 Diabetes Mellitus