azithromycin / Generic mfg. - LARVOL DELTA

Assessing Knowledge, Attitude, and Practices of Dentists on Antibiotic Use for Pediatric Dental Infections in Bangladesh: A Cross-Sectional Study. (PubMed, Health Sci Rep) - "Amoxicillin, azithromycin, and clindamycin were the antibiotics most commonly prescribed. Awareness of AMR is high, but this awareness does not consistently translate into cautious prescribing. Structured antibiotic stewardship guidance for paediatric dental practice is needed."

Journal • Observational data • Infectious Disease • Pediatrics

Transient Reactive Cervical Lymphadenopathy Following PRP-Based Regenerative Procedures: A Two-Case Series (EADV 2026) - "Following a second PRP-only session performed six weeks later, the patient experienced recurrent cervical lymphadenopathy and self-administered azithromycin because of concern regarding recurrence; symptoms again resolved within three to four weeks...Conclusions Clinicians performing PRP-based aesthetic procedures should be aware of transient cervical lymphadenopathy as a rare but benign and self-limiting adverse event. Appropriate clinical assessment and patient reassurance are essential to prevent over-investigation and overtreatment."

Clinical • Aesthetic Medicine • Alopecia • Dermatology • Immunology • Infectious Disease

Reactive Infectious Mucocutaneous Eruption Following a Respiratory Infection in an Adolescent: A Case Report. (PubMed, Cureus) - "The patient improved over the following several days after initiation of azithromycin, continuation of clindamycin, and wound care for scrotal and oral mucosal lesions. Differentiating RIME from other mucocutaneous disorders is vital to prescribing proper treatment and preventing further systemic effects. This case underscores the importance of considering Mycoplasma as a potential etiology in patients presenting with mucocutaneous lesions and conjunctivitis following a previous respiratory infection."

Journal • Conjunctivitis • Dermatology • Infectious Disease • Inflammation • Influenza • Mucositis • Novel Coronavirus Disease • Ocular Infections • Ocular Inflammation • Ophthalmology • Pediatrics • Pneumonia • Respiratory Diseases • Respiratory Syncytial Virus Infections • Steven-Johnson Syndrome • Stomatitis

Papulopustular and Rosacea-like Eruptions During BRAF/MEK and EGFR Inhibitor Therapy: A Case Series (EADV 2026) - "She received two cycles of azithromycin 500 mg daily for three consecutive days, together with topical erythromycin. Due to incomplete response, oral doxycycline and topical ivermectin were subsequently introduced, leading only to partial benefit...The third patient was a 66-year-old man treated with FOLFIRI chemotherapy, including folinic acid, 5-fluorouracil, and irinotecan, combined with the EGFR inhibitor panitumumab for hepatic recurrence of sigmoid-rectal adenocarcinoma...Treatment with ketoconazole washes and topical clindamycin twice daily resulted in partial clinical improvement...The recurrence observed in our first patient after switching from vemurafenib/cobimetinib to dabrafenib/trametinib further suggests a class-related susceptibility to BRAF/MEK pathway inhibition rather than a reaction to a single agent...Oral tetracyclines, topical antibiotics, ivermectin, antiseptic or antifungal washes, and anti-inflammatory topical treatments may be considered,..."

Clinical • Acne Vulgaris • Colorectal Adenocarcinoma • Dermatitis • Dermatology • Immunology • Melanoma • Rectal Adenocarcinoma • Rosacea • Solid Tumor

Retrospective study of Mycoplasma genitalium antimicrobial resistance: Analysis with previous clinic data (EADV 2026) - "European IUSTI guidelines recommend nucleic acid amplification testing (NAAT) for accurate MG diagnosis and suggest an extended azithromycin (AZI) regimen as the primary treatment, with moxifloxacin (MOXI) as second line treatment and minocycline (MINO) as third line treatment. Furthermore, there has been a significant increase in macrolide resistance, accompanied by the new emergence of moxifloxacin resistance. These results highlight the importance of testing all patients who visit our clinic for MG, with a focused emphasis on monitoring resistance to address emerging challenges in treatment efficacy."

Retrospective data • Infectious Disease • Inflammation

Upadacitinib in granulomatous vulvitis: learning from a challenging case (EADV 2026) - "After Crohn's disease had been excluded, she received multiple treatments including azithromycin, minocycline, methotrexate, infliximab, adalimumab, ustekinumab, vedolizumab, hyperbaric oxygen therapy, systemic corticosteroids and metronidazole, with only partial improvement. In our case, upadacitinib at a dose of 30 mg/day proved effective in controlling lesions and improving pain and quality of life in severe granulomatous vulvitis, suggesting that it may represent a therapeutic option worth exploring. However, the development of synechiae following inflammation reduction required dose adjustment and highlighted the importance of multidisciplinary management in this condition."

Clinical • Crohn's disease • Gastroenterology • Inflammation • Inflammatory Bowel Disease

Effectiveness of Pristinamycin and Minocycline against Fluoroquinolone-resistant Mycoplasma genitalium Infection: A Study of Consecutive Patients Attending a Sexual Health Clinic (EADV 2026) - "Increasing antimicrobial resistance, particularly to first-line azithromycin (macrolide-resistant M. genitalium ) but also to second-line moxifloxacin (fluoroquinolone-resistant M. genitalium ), has created an urgent need for effective alternative treatments. Despite this limitation, these findings suggest that minocycline may be a potential alternative to pristinamycin for patients with dual resistant M. genitalium infection, although these results should be interpreted with caution, given the small sample size. Nevertheless, given minocycline's availability and lower cost compared with pristinamycin, it may be considered a reasonable third-line treatment option."

Clinical • Infectious Disease • Inflammation

Photo- and Heat-Induced Drug Eruption Associated with Combined Trametinib and Tebentafusp Therapy in Metastatic Uveal Melanoma: A Case Report (EADV 2026) - "Despite multiple systemic courses of doxycycline and azithromycin associated with topical corticosteroids and antibiotic preparations containing neomycin and hydrocortisone acetate, the eruption progressively worsened and disseminated to the trunk and limbs...Systemic corticosteroid therapy with gradual tapering, combined with topical metronidazole-containing preparations, resulted in significant improvement of the eruption and pruritus. Owing to progressive metastatic disease, treatment with Dacarbazine was initiated...This case highlights the importance of early recognition of uncommon cutaneous adverse reactions in patients receiving targeted therapies and immunotherapy, as prompt multidisciplinary management may improve patient outcomes and therapeutic decision-making. Furthermore, the observation raises important questions regarding potential synergistic mechanisms between trametinib- and tebentafusp-induced immune pathways, the prognostic significance of cutaneous..."

Case report • Clinical • Metastases • Contact Dermatitis • Cutaneous Lupus Erythematosus • Cutaneous Melanoma • Dermatitis • Eye Cancer • Immunology • Inflammatory Arthritis • Lupus • Melanoma • Pruritus • Solid Tumor • Uveal Melanoma

Reactive Infectious Mucocutaneous Eruption (RIME) Successfully Treated With Upadacitinib in Three Adolescents (EADV 2026) - "Management remains non-standard, relying on supportive care, antibiotics, and heterogeneous systemic immunomodulators including corticosteroids, cyclosporine, intravenous immunoglobulin, or tumor necrosis factor inhibitors...He received azithromycin x 5 days, clobetasol propionate 0.05% ointment, and upadacitinib 15 mg daily x 14 days...Case 3: A 13-year-old female presented 3 weeks post infectious respiratory symptoms and empiric treatment with amoxicillin, clarithromycin, doxycycline, and systemic corticosteroid...She received upadacitinib 15 mg daily x 14 days, lidocaine mouthwash, and zinc supplementation...Furthermore it is fast-acting, non-injectable, outpatient-administered, and does not require laboratory monitoring. Prospective studies should validate efficacy, refine dosing/timing, assess long-term safety (including infection reactivation), and compare against standards—potentially establishing upadacitinib as first-line for suitable patients without..."

Conjunctivitis • Hematological Disorders • Infectious Disease • Mucositis • Ocular Infections • Ocular Inflammation • Ophthalmology • CRP

Ecotoxicity and carbon footprint of commonly used antibiotics: Moving towards environmentally sustainable use. (PubMed, Infect Dis Now) - "Although discrepancies between CF and eco-toxicity limit recommendations, these two parameters may guide decisions to reduce environmental footprint in a One-Health approach."

Journal

Herpes Zoster Ophthalmicus Post-Botox Injection: A Case Report (EADV 2026) - "Despite azithromycin and ibuprofen, the symptoms persisted. Conclusion This case highlights a rare occurrence of herpes zoster ophthalmicus following Botulinum toxin type A (BoNT-A) injection. Timely diagnosis and appropriate antiviral therapy such as acyclovir are essential in managing this condition effectively."

Case report • Clinical • Herpes Zoster • Ophthalmology • Varicella Zoster

Chlamydia prescribing trends in Australia before and after a national guideline update: a retrospective study of sentinel surveillance data, 2015-2025. (PubMed, Sex Health) - "Doxycycline prescribing for chlamydia has increased with corresponding declines in azithromycin use following the 2022 Australian treatment guideline change. Setting-specific implementation strategies may accelerate evidence uptake for future guideline updates."

Journal • Retrospective data • Infectious Disease • Urology

Efficacy of Intermittent, Cyclical Azithromycin in Pediatric Pityriasis Lichenoides: A Case Series (EADV 2026) - "Although macrolides, specifically erythromycin and to a lesser extent clarithromycin, are widely accepted therapies for children and adults, data regarding the use of azithromycin remain limited...Over the course of the disease, she did not respond to topical steroids and oral amoxicillin-clavulanate 45 mg/kg/day for 7 days...This approach reduces the cumulative dose, duration of drug exposure, and caregiver burden compared with daily dosing. Further data are required to establish the safety profile and optimal dosing regimen."

Clinical • Infectious Disease • Inflammation • Pediatrics

A Unique Case of Undertreated Confluent and Reticulated Papillomatosis Persisting for 10 Years, Treated with Azithromycin (EADV 2026) - "Although minocycline is the first-line treatment, it has a broad side effect profile and is also contraindicated in pregnancy. This case emphasises the need to select the correct modality of treatment, as CARP is a chronic disease which may continue for many years, causing cosmetic concerns for the patients. Furthermore, due to their favourable safety profiles and possible use in vulnerable patients, macrolides might be the preferred first-line treatment in the future."

Clinical • Pruritus

Unilateral facial dermatitis induced by topical nepafenac mimicking infectious folliculitis (EADV 2026) - "Empirical azithromycin therapy produced no clinical improvement. Conclusion This case highlights nepafenac-induced facial dermatitis as a diagnostic pitfall capable of clinically and histologically mimicking infectious disease. Careful reassessment of drug exposure and clinicopathological correlation remain essential in unilateral facial eruptions, particularly when microbiological investigations are negative and clinical evolution is atypical."

Dermatitis • Dermatology • Dermatopathology • Discoid Lupus Erythematosus • Immunology • Infectious Disease • Inflammatory Arthritis • Lupus • Ophthalmology • Skin Cancer • Squamous Cell Carcinoma

Beyond simple folliculitis.lupus folliculitis in a male patient:A diagnostic dilemma (EADV 2026) - "The patient had failed multiple topical and systemic treatments, including antibiotics(metronidazole,ampicillin,azithromycin,clindamycin,doxycycline) and retinoids(oral and topical isotretinoin) for treating acne rosacea and folliculitis.Cutaneous examination revealed hyperpigmentation involving his malar(butterfly) region,multiple milia on zygomatic region,fine wrinkles in periocular region,there were multiple erythematous plaques studded with pustules distributed asymmetrically in his beared area of face and neck,with few areas of scarring,however no such lesion was present on his scalp,and his mucosae were healthy looking.All laboratory parameters were noramal including ANA and anti dsDNA.skin biopsy done for histopathological evaluation showed acanthosis with slight hyperkeratosis along with follicular plugging.upper dermis showed solar elastosis along with dense lymphocytic infiltrate no neutrophils or eosinophils were seen,lymphocytic aggregates were seen around..."

Clinical • Acne Vulgaris • Cutaneous Lupus Erythematosus • Immunology • Inflammatory Arthritis • Lupus • Rosacea

Reactive Infectious Mucocutaneous Eruptions: A retrospective case series (EADV 2026) - "Two of them experienced recurrent relapses, one of whom demonstrated subjective improvement after commencement of prophylactic azithromycin...At present there is no consensus guidance on optimal management. We highlight the urgent need for paediatric-specific clinical guidelines and further research to establish optimal evidence-based management and prophylactic strategies."

Retrospective data • CNS Disorders • Immunology • Infectious Disease • Inflammation • Mucositis • Novel Coronavirus Disease • Pneumonia • Respiratory Diseases • Steven-Johnson Syndrome

A Preventable Source of Cutaneous Mycobacterium abscessus Infection: Contaminated Insulin Syringes in a Patient with Diabetes Mellitus (EADV 2026) - "Case Presentation A 48-year-old woman with type 2 diabetes mellitus treated with insulin glargine, metformin, and weekly semaglutide presented with a two-month history of painful inflammatory lesions involving both upper extremities...Multiple empirical antibiotic regimens, including dicloxacillin, clindamycin, and ciprofloxacin, were ineffective...Broth microdilution susceptibility testing according to Clinical and Laboratory Standards Institute guidelines demonstrated susceptibility to amikacin, clarithromycin, azithromycin, tigecycline, omadacycline, and tedizolid; intermediate susceptibility to imipenem and cefoxitin; and resistance to fluoroquinolones and linezolid...Negative stains and molecular assays do not exclude the diagnosis, and prolonged mycobacterial culture remains essential. This case highlights the importance of species identification and antimicrobial susceptibility testing to guide targeted multidrug therapy."

Clinical • Aesthetic Medicine • Diabetes • Infectious Disease • Inflammation • Metabolic Disorders • Mood Disorders • Nontuberculous Mycobacterial Disease • Respiratory Diseases • Type 2 Diabetes Mellitus

Complete Remission of Dissecting Cellulitis of the Scalp with Adalimumab in an Adolescent with Early-Onset Disease: Biologic Therapy Beyond Hidradenitis Suppurativa (EADV 2026) - "Previous treatments included azithromycin, oral isotretinoin (20 mg/day for 5 months), clindamycin (300 mg twice daily for 7 days), and doxycycline (100 mg/day for 2 months), with limited response. Conclusion This case supports the concept of a shared pathogenic pathway within the follicular occlusion tetrad and highlights the potential efficacy of adalimumab in treating not only hidradenitis suppurativa but also severe dissecting cellulitis of the scalp.While the benefit of biologic therapy in hidradenitis suppurativa is well established, its role in dissecting cellulitis remains less documented. Our findings suggest that early biologic intervention may effectively control inflammation across the disease spectrum and significantly improve patient quality of life, although established scarring remains irreversible."

Clinical • Acne Vulgaris • Alopecia • Dermatology • Fibrosis • Hidradenitis Suppurativa • Immunology • Inflammation

Extrapulmonary Nontuberculous Mycobacteria (EP-NTM) Infection in a 66-year-old patient - A Case Report (EADV 2026) - "Combination therapy with azithromycin (250 mg/day), rifampicin (600 mg/day), and ethambutol (15 mg/kg/day) was initiated...However, due to persistently positive sputum cultures throughout the treatment course, an extension of the antimicrobial regimen with amikacin and clofazimine is currently being considered...Primary cutaneous manifestations may occur in the complete absence of pulmonary symptoms and may also present with a disseminated distribution pattern, in contrast to the sporotrichoid distribution typically observed in other nontuberculous mycobacteria infections. This case highlights the crucial role of dermatology in diagnosing extrapulmonary nontuberculous mycobacteria infections."

Case report • Clinical • Nontuberculous mycobacteria • Cytomegalovirus Infection • Epstein-Barr Virus Infections • Hepatology • Infectious Disease • Nontuberculous Mycobacterial Disease • Respiratory Diseases • CD4 • CD8

RCT: Impact of Pharmacist Led Multidisciplinary Deprescribing Strategy in Patients With Respiratory Tract Infections (clinicaltrials.gov) - P=N/A | N=200 | Enrolling by invitation | Sponsor: Xi'an Jiaotong University

New trial • Infectious Disease • Respiratory Diseases

Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye (clinicaltrials.gov) - P1/2 | N=50 | Completed | Sponsor: Ehab Mohamed Elsayed Mohamed Saad | Not yet recruiting ➔ Completed

Trial completion • Dry Eye Disease • Ophthalmology • CXCL8

CF-HEAR: Rates of Hearing and Vestibular Abnormalities in People with Cystic Fibrosis Exposed to Ototoxic Therapies (NACFC 2026) - "Participants included PwCF ages 6 years and older currently or recently prescribed an oral macrolide (azithromycin) and/or an inhaled or intravenous (IV) aminoglycoside (amikacin or tobramycin)...In the three years prior to enrollment, 89% of PwCF were prescribed chronic azithromycin, 38% inhaled tobramycin, and 15% IV tobramycin... Utilizing a standardized screening approach for testing hearing and vestibular abnormalities in PwCF exposed to ototoxic medications, we identified a significantly higher proportion of PwCF with abnormalities than is reported in CF Foundation patient registry data. As the lifespan of PwCF continues to increase, this underscores the vital importance of a standardized, easily accessible approach to assessing this in PwCF to identify opportunities for intervention to improve quality of life."

Cystic Fibrosis • Genetic Disorders • Immunology • Otorhinolaryngology • Respiratory Diseases

Utility of Lipoarabinomannan as a Marker of NTM Lung Infection in Cystic Fibrosis: Preliminary Results from the Prospective Analysis of urINe LAM to Eliminate NTM Sputum Screening (PAINLESS) Trial (NACFC 2026) - P | "In the cohort of pwCF receiving azithromycin during the study period, the urine LAM test identified all subjects with a positive NTM culture... Urine LAM is a non-invasive culture-independent biomarker that identifies pwCF at both high and low risk for positive NTM sputum cultures. Results from the LAM analysis support the conclusion that pwCF are frequently infected with NTM at higher rates than reported based on sputum cultures. If validated, LAM could serve as an adjunct to sputum cultures for routine NTM screening, and replace cultures in low-risk individuals unable to produce sputum."

Clinical • Cystic Fibrosis • Genetic Disorders • Immunology • Infectious Disease • Nontuberculous Mycobacterial Disease • Respiratory Diseases

Two Morphotypes, Two Strategies: Metabolic Drivers of Nitric Oxide Tolerance in Mycobacterium abscessus (NACFC 2026) - " We investigated whether MABR has a survival advantage over MABS under infection-mimicking conditions: zinc limitation, oxygen deprivation, nitric oxide exposure, and treatment with the clinically relevant antibiotics amikacin and azithromycin. NO is produced by host immune cells, serves as a key antimicrobial effector and has also been administered therapeutically in CF care. Here we demonstrate that MABR exhibits substantial tolerance to NO, mediated by the PAA pathway. Given that NO is both naturally generated during infection and used as an inhaled therapeutic in CF, bacterial metabolism may influence the efficacy of NO-based treatment and could create selective pressure favoring the emergence of MABR."

Cystic Fibrosis • Genetic Disorders • Immunology • Infectious Disease • Inflammation • Respiratory Diseases