AB012 / Aronora - LARVOL DELTA

The Oxylipin Dependent Quorum Sensing System enhances Pseudomonas aeruginosa dissemination during burn-associated infection. (PubMed, PLoS Pathog) - "In vivo, AB012 reduced bacterial burden and systemic spread following burn injury. Collectively, these findings reveal that P. aeruginosa exploits host-derived oleic acid to activate ODS and enhance virulence, and they highlight OdsA as a promising target for therapeutic intervention to prevent sepsis in burn patients."

Journal • Infectious Disease • Septic Shock • Thermal Injury

AB012. A phase III randomized trial of gross total resection versus possible resection of fluid-attenuated inversion recovery (FLAIR) hyperintensity lesion on magnetic resonance image for newly diagnosed supratentorial glioblastoma (JCOG2209). (PubMed, Chin Clin Oncol) - "Registry number: jRCT1031230245. Date of registration: 19/July/2023. Date of first participant enrollment: 28/July/2023."

Clinical • Clinical protocol • Journal • MRI • P3 data • Brain Cancer • Cardiovascular • CNS Tumor • Cognitive Disorders • Glioblastoma • Oncology • Solid Tumor