ALTM0230
/ Alethio Therapeutics
- LARVOL DELTA
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May 12, 2026
DEVELOPMENT OF A G6B DIRECTED ANTIBODY DRUG CONJUGATE FOR THE TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS
(EHA 2026)
- "Development of antibodies capable of G6B binding and internalisation, alongside screening of toxic payloads, led to the discovery of ALTM0230, an exatecan ADC...2023 Cancer Discov. 13, 364"
ADC • Essential Thrombocythemia • Hematological Disorders • Hematological Malignancies • Myelofibrosis • Myeloproliferative Neoplasm • Polycythemia Vera • Thrombocytosis • CALR • JAK2
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