Albunorm (human albumin) / Octapharma - LARVOL DELTA

Comparative Characterisation of Five Plasma-Derived Human Serum Albumin Preparations: Structural Integrity, Functional Properties, and Quality Attributes. (PubMed, Pharmaceuticals (Basel)) - "Objective: To comprehensively characterise five commercial plasma-derived albumin preparations (VIALEBEX®, ALBUNORM®, ALBUREX®, FLEXBUMIN®, ALBUTEIN®) using multiple analytical approaches to assess structural integrity, post-translational modifications, functional properties and purity. VIALEBEX® demonstrated greater structural integrity and functional properties despite a higher polymer content, suggesting complex quality relationships beyond simple aggregation. The preservation of structural integrity and higher redox state of VIALEBEX® could be relevant considerations when selecting a product for clinical or pre-clinical use."

Journal

Effect of Selected Crystalloid and Colloid Solutions on Coagulation Status Evaluated by Rotational Thromboelastometry and Platelet Function Analyser: An in vitro Study. (PubMed, Transfus Med Hemother) - "This in vitro study assessed the impact of Plasma-Lyte, albunorm 5%, and Gelaspan 4% solutions on primary and secondary haemostasis using rotational thromboelastometry and platelet function analyser...Gelaspan 4% adversely affected the propagation phase of coagulation, maximal strength and elasticity of the coagulum, and the level of functional fibrinogen. All solutions adversely affected platelet function in primary haemostasis, with Plasma-Lyte showing the least effect."

Journal • Preclinical