λcarrageenan nasal spray
/ University of Birmingham
- LARVOL DELTA
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June 02, 2021
Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2.
(PubMed, Adv Mater)
- "From this data, a mechanism for both prophylaxis and prevention is proposed; where entrapment within a polymeric coating sterically blocks virus uptake into the cells, inactivating the virus, and allowing clearance within the viscous medium. As such, a fully preventative spray is formulated, targeted at protecting the lining of the upper respiratory pathways against SARS-CoV-2."
Journal • Infectious Disease • Novel Coronavirus Disease • Respiratory Diseases
November 19, 2020
Anti-COVID nasal spray formulated at University of Birmingham, UK is ’ready for use in humans’
(PRNewswire)
- "A nasal spray to provide protection against the COVID-19 virus has been formulated by researchers at the University of Birmingham, UK....The formulation consists of an antiviral agent, λcarrageenan....Studies showed the formulation can deliver significant (minimum of p<0.05) suppression of infection in cell cultures challenged by live virus compared to untreated controls....University of Birmingham Enterprise has filed a patent application covering the sprayable antiviral formulation for use as an oral, nasal or multi-surface spray, and is now seeking to license the patent to an organisation that is committed to manufacturing..."
Patent • Preclinical • Infectious Disease • Novel Coronavirus Disease
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