λcarrageenan nasal spray / University of Birmingham - LARVOL DELTA

Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2. (PubMed, Adv Mater) - "From this data, a mechanism for both prophylaxis and prevention is proposed; where entrapment within a polymeric coating sterically blocks virus uptake into the cells, inactivating the virus, and allowing clearance within the viscous medium. As such, a fully preventative spray is formulated, targeted at protecting the lining of the upper respiratory pathways against SARS-CoV-2."

Journal • Infectious Disease • Novel Coronavirus Disease • Respiratory Diseases

Anti-COVID nasal spray formulated at University of Birmingham, UK is ’ready for use in humans’ (PRNewswire) - "A nasal spray to provide protection against the COVID-19 virus has been formulated by researchers at the University of Birmingham, UK....The formulation consists of an antiviral agent, λcarrageenan....Studies showed the formulation can deliver significant (minimum of p<0.05) suppression of infection in cell cultures challenged by live virus compared to untreated controls....University of Birmingham Enterprise has filed a patent application covering the sprayable antiviral formulation for use as an oral, nasal or multi-surface spray, and is now seeking to license the patent to an organisation that is committed to manufacturing..."

Patent • Preclinical • Infectious Disease • Novel Coronavirus Disease