BB-205
/ Bright Biologics
- LARVOL DELTA
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March 26, 2025
The anti-tumor activity of a novel anti-Her2 and anti-c-Met bispecific antibody-drug conjugate
(AACR 2025)
- "Its cytotoxic potency was comparable to Trastuzumab-MMAE (T-MMAE) in Her2-high expressing cancer cells and to Telisotuzumab vedotin (Teliso-V) in c-Met-high expressing cancer cells. The novel anti-Her2/anti-c-Met bispecific ADC BB-205 demonstrates superior anti-tumor activity in preclinical studies. BB-205 shows promising therapeutic potential as a first-in-class ADC drug candidate."
Genito-urinary Cancer • Kidney Cancer • Oncology • Pancreatic Cancer • Renal Cell Carcinoma • Solid Tumor • MET
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