RIG-101
/ RIGImmune
- LARVOL DELTA
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June 12, 2025
Antiviral effects of a RIG-I agonist (RIG101) against human rhinovirus in mice and differentiated bronchial epithelium from asthmatics
(ERS 2025)
- "Prophylactic treatment of RIG-101 NEED TM demonstrates potent antiviral effects against HRV in vivo and i n vitro , suggesting potential utility in protecting against virally-induced asthma exacerbations."
Preclinical • Asthma • Immunology • Infectious Disease • Respiratory Diseases • CXCL10 • CXCL8
June 01, 2024
Effects of an anti-viral interferon booster, RIG-I agonist (RIG-101), on influenza infection in vitro and in vivo
(ERS 2024)
- "The antiviral effect was comparable or superior to oseltamivir. RIG-101 was found to show significant induction of interferon signalling, and potent antiviral effects against influenza in vitro and in vivo. This suggests that topical prophylactic treatment of RIG-101 has potential to show viral prevention efficacy against influenza infection."
Preclinical • Infectious Disease • Influenza • Novel Coronavirus Disease • Respiratory Diseases • CXCL10
June 01, 2024
Adjuvancy effects of a RIG-I agonist (RIG101) on H1N1 HA antigen intranasally vaccinated mice and human nasal epithelium/PBMCs co-culture
(ERS 2024)
- "RIG101, a RIG-I agonist, is promising adjuvant to boost mucosal vaccine effects against respiratory virus."
Preclinical • Infectious Disease • Inflammation • Influenza • Novel Coronavirus Disease • Respiratory Diseases
June 01, 2024
Pan-antiviral effects of RIG-I agonist (RIG-101) against respiratory syncytial virus and human rhinovirus in nasal epithelium in vitro and mice in vivo
(ERS 2024)
- "Prophylactic treatment of RIG-101 nanoemulsion demonstrate potent antiviral activities against HRV and RSV, suggesting that topical RIG101 delivered to nasal tract can induce sterilising immunity."
Preclinical • Asthma • Chronic Obstructive Pulmonary Disease • Immunology • Infectious Disease • Respiratory Diseases • Respiratory Syncytial Virus Infections • CXCL10
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