triamcinolone acetonide / Generic mfg. - LARVOL DELTA

Vogt-Koyanagi-Harada Disease in which Poliosis and Alopecia Occurred after a Long Period of Time. (PubMed, Acta Dermatovenerol Croat) - "The patient was initially diagnosed with alopecia universalis and received 15 intradermal injections of 1 mg of triamcinolone acetonide to the same region...Treatment was started with oral prednisolone at a dose of 30 mg per day, with the dose gradually reduced by 5 mg every 2 weeks...Unfortunately, we have observed no growth of scalp hair. The patient continues to attend follow-up, with special attention to the potential onset of vitiligo."

Journal • Alopecia • Dermatology • Immunology • Inflammation • Ocular Inflammation • Ophthalmology • Pain • Uveitis • Vitiligo

Efficacy of Intramuscular Steroid Injection for Chronic Cough. (clinicaltrials.gov) - P1 | N=40 | Recruiting | Sponsor: Medical University of South Carolina | Trial completion date: Dec 2025 ➔ Jun 2026 | Trial primary completion date: May 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • Chronic Cough • Cough • Otorhinolaryngology • Pulmonary Disease • Respiratory Diseases

PROTECT: Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields (clinicaltrials.gov) - P2 | N=58 | Recruiting | Sponsor: Memorial Sloan Kettering Cancer Center | Trial completion date: Jul 2025 ➔ Jul 2026 | Trial primary completion date: Jul 2025 ➔ Jul 2026

Adverse events • Trial completion date • Trial primary completion date • Brain Cancer • Glioblastoma • Oncology • Solid Tumor

Reducing Early Intraocular Pressure Spikes: The Role of Low-Dose Triamcinolone Acetonide Post-Ahmed Glaucoma Valve Implantation (ACS-CLINCON 2025) - "Abstract is embargoed at this time."

Glaucoma • Ophthalmology

Management of oral sub-mucous fibrosis using platelet-rich plasma and triamcinolone with hyaluronidase. (PubMed, Bioinformation) - "Patients diagnosed with grade II and III oral submucous fibrosis participated in this study. Results show that intralesional PRP was more effective than the combination of triamcinolone acetonide and hyaluronidase in the management of oral submucous fibrosis."

Clinical • Journal • Fibrosis • Immunology

Preparation and In Vitro Characterization of Triamcinolone Acetonide-Loaded Lipid Liquid Crystal Nanocarriers for Ocular Delivery. (PubMed, Adv Pharm Bull) - "This study aimed to develop sustained-release triamcinolone acetonide (TA) formulations using lipid liquid crystals (LLCs) for ocular drug delivery and to characterize the designed formulations. PLM analysis revealed the presence of hexosomes and cubosomes, indicating that an increase in hexosomes contributed to a more uniform drug release from the formulations. Overall, the study findings suggest that liquid crystalline carriers can be a promising formulation for sustained ocular drug delivery of TA."

Journal • Preclinical

Vulvar Crohn disease: A case report. (PubMed, SAGE Open Med Case Rep) - "She was experiencing painful vulvar fissures, which ultimately resulted in a diagnosis of vulvar Crohn's disease. The patient's symptoms had resolved at the most recent follow-up visit with treatment, including adalimumab 40 mg, metronidazole 500 mg, and intralesional triamcinolone acetonide injections."

Journal • Crohn's disease • Dermatology • Gastroenterology • Genetic Disorders • Hidradenitis Suppurativa • Immunology • Inflammatory Bowel Disease • Pain • Psoriasis

Comparison of Subconjunctival Triamcinolone with Topical Prednisolone for Routine Anti-Inflammatory Prophylaxis in Manual Small Incision Cataract Surgery: A Single-Center, Randomized Controlled Trial Pilot Protocol. (PubMed, Clin Ophthalmol) - P=N/A | "Subconjunctival injection of triamcinolone acetonide (TA) is an effective method to prevent postoperative inflammation in phacoemulsification eyes...Intracameral moxifloxacin 0.15% is injected at the end of surgery in both groups...The objective of this study is to evaluate the safety and efficacy of a single subconjunctival TA injection compared to standard postoperative topical therapy using PA 1% in eyes undergoing MSICS. Clinicaltrials.gov: NCT05248139; Protocol issue date: August 9, 2024; Amendment number: 02."

Journal • Cataract • Inflammation • Macular Edema • Ocular Infections • Ocular Inflammation • Ophthalmology • Uveitis

Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery (clinicaltrials.gov) - P2 | N=28 | Not yet recruiting | Sponsor: Rutgers, The State University of New Jersey | Initiation date: Feb 2025 ➔ Jul 2025

Trial initiation date • Otorhinolaryngology

Efficacy of combined topical nepafenac 0.3% with suprachoroidal injection of triamcinolone acetonide using a modified custom needle in pseudopkakic cystoid macular edema. (PubMed, BMC Ophthalmol) - P1 | "Combined SCTA using this modified custom needle with topical nepafenac 0.3% resulted in better anatomical and functional results in PCME patients compared to topical nepafenac 0.3% alone. The study was prospectively registered with clinical trial.gov ID (NCT04690608) in 27-12-2020."

Clinical • Journal • Macular Edema • Ophthalmology

Intralesional Triamcinolone Alone Vs. Combined Platelet-Rich Plasma for Keloid Treatment. (PubMed, J Coll Physicians Surg Pak) - "Combining intralesional triamcinolone acetonide with PRP is significantly more effective than corticosteroid monotherapy in the treatment of keloids."

Clinical • Journal • Dermatology • Fibrosis

Predictive value of subacromial motion metrics for the effectiveness of ultrasound-guided dual-target injection: a longitudinal follow-up cohort trial. (PubMed, Insights Imaging) - P=N/A | "Dynamic ultrasound metrics predict injection success and pain recurrence in impingement. Dual-target injections offer a longer duration of effectiveness than standard injections. Future research should assess deep learning's predictive value in adhesive capsulitis."

Journal • Musculoskeletal Diseases • Musculoskeletal Pain • Orthopedics • Pain

Intralesional corticosteroid in the treatment of periorbital Kimura disease: a case report. (PubMed, Orbit) - "Following incisional biopsy, the patient received monthly intralesional corticosteroid injections (2 ml of triamcinolone acetonide, 20 mg/ml) for six months. There was a significant reduction in mass size, with no recurrence over a one-year follow-up period. This case highlights the effectiveness of intralesional corticosteroids as a minimally invasive treatment option for peri-orbital KD, particularly when complete surgical resection is not feasible."

Journal • Eosinophilia • Glomerulonephritis • Inflammation • Nephrology • Pain • Renal Disease

Effectiveness and Safety of Intravitreal Brolucizumab for Diabetic Macular Edema After Vitrectomy: A Before-and-After Study at a Specialized Center in Japan. (PubMed, Clin Ophthalmol) - "If CST did not improve after the last IVBr injection, treatment was switched to intravitreal triamcinolone acetonide injection (IVTA), sub-Tenon's triamcinolone acetonide (STTA) injection, or intravitreal faricimab (IVFa)...Our findings demonstrated partial efficacy of IVBr in managing DME in vitrectomized eyes. However, variable responses often necessitate supplementary treatments to achieve therapeutic goals."

Journal • Diabetes • Diabetic Macular Edema • Inflammation • Metabolic Disorders • Ophthalmology

Incidence of and Risk Factors for Silicone Oil-Associated Cystoid Macular Edema After Pars Plana Vitrectomy. (PubMed, J Vitreoretin Dis) - "Compared with untreated groups, the frequency of CME regression was not influenced by the administration of sub-Tenon triamcinolone acetonide (75.0% vs 75.0%; P = 1.00), prednisolone acetate eyedrops (75.0% vs 75.0%; P = 1.00), or ketorolac eyedrops (71.4% vs 76.9%; P = .79). The viscosity of the SO used for vitreous tamponade in RD repair may play a role in the development of CME, with lighter grade oil increasing the risk for disease. Furthermore, SO removal alone potentially leads to a prominent reduction in CME in most cases."

Journal • Macular Edema • Ophthalmology • Retinal Disorders

Visual Outcomes and Safety Profile of "Dropless Vitrectomy" for Epiretinal Membranes. (PubMed, Clin Ophthalmol) - "Group 1 (N = 139) received a triamcinolone acetonide-moxifloxacin (Tri-Moxi) intravitreal injection at the conclusion of surgery, and Group 2 (N = 139) had postoperative standard topical antibiotic-steroid therapy...Intravitreal Tri-Moxi can be used as a viable treatment option for managing inflammation and preventing infection after epiretinal membrane removal by pars plana vitrectomy. Tri-Moxi group demonstrated superior anatomical outcomes and comparable functional outcomes while simplifying postoperative care and reducing the occurrence of cystoid macular edema compared to standard topical therapy."

Journal • Cardiovascular • Glaucoma • Infectious Disease • Inflammation • Macular Edema • Ocular Infections • Ophthalmology • Retinal Disorders

Comparison of Corticosteroid Injection, Nighttime Splinting, or Their Combination for Initial Treatment of Moderate-to-Severe Carpal Tunnel Syndrome (clinicaltrials.gov) - P=N/A | N=318 | Not yet recruiting | Sponsor: Yun Qian

New trial • Musculoskeletal Pain

Comparison of Initial Treatment for Carpal Tunnel Syndrome Related to Rheumatic Diseases: Corticosteroid Injection Versus Nighttime Splinting (clinicaltrials.gov) - P=N/A | N=248 | Not yet recruiting | Sponsor: Yun Qian

New trial • Musculoskeletal Pain • Rheumatology

Efficacy and Safety of Intralesional 5-Fluorouracil and Triamcinolone Acetonide in Keloids and Hypertrophic Scars (clinicaltrials.gov) - P=N/A | N=41 | Completed | Sponsor: Maharajgunj Medical Campus

New trial • Fibrosis

Biological Response to Platelet-rich Plasma and Corticosteroid Injections (clinicaltrials.gov) - P1/2 | N=23 | Terminated | Sponsor: University of Missouri-Columbia | N=70 ➔ 23 | Trial completion date: Dec 2025 ➔ Jun 2025 | Recruiting ➔ Terminated | Trial primary completion date: Dec 2025 ➔ Jun 2025; Principal Investigator is Retiring.

Enrollment change • Trial completion date • Trial primary completion date • Trial termination • Immunology • Osteoarthritis • Pain • Rheumatology • CCL3 • CXCL8 • IL1R1 • IL4

Intraocular Inflammation Following Faricimab Intravitreal Injection Treated With Sub-tenon Triamcinolone Acetonide Injection. (PubMed, Cureus) - "In this study, IOI was managed with a STTA injection during the early stage of uveitis. Severe inflammation can lead to complications such as posterior iris synechia."

Journal • Age-related Macular Degeneration • Diabetic Macular Edema • Inflammation • Macular Degeneration • Ocular Inflammation • Ophthalmology • Retinal Disorders • Uveitis

Clinical and Functional Outcomes of Intra-articular Hyaluronic Acid Versus Corticosteroids in Knee Osteoarthritis: A Comparative Study. (PubMed, Cureus) - "The subjects were randomised to receive either intra-articular CS (40 mg triamcinolone acetonide with 2% lignocaine) or HA (6 ml, 48 mg sodium hyaluronate). Similarly, the HA group's WOMAC score was significantly better (53.4 ± 9.91 vs. 64.2 ± 6.8, p = 0.001).  While both HA and CS injections effectively reduce pain and improve functionality of the knee joint, HA provides sustained pain relief and functional improvement beyond the short-term effects of CS. These findings support the use of HA as a preferred option for managing mild-to-moderate knee OA."

Journal • Immunology • Inflammation • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Comparing the Effect of Intralesional 5-Fluorouracil (5-FU) Alone Versus Intralesional 5-FU Combined With Triamcinolone Acetonide for Keloid Treatment. (PubMed, Cureus) - "Both groups are efficacious for the treatment of keloid; however, the combination of 5-FU and TCA revealed greater efficacy, and it was significantly better than 5-FU alone. The results were again significantly better in terms of efficacy in the male gender and those who had keloids for more than one year."

Journal • Cardiovascular • Dermatology • Diabetes • Fibrosis • Hypertension • Metabolic Disorders

Concomitant therapy of surgical shave excision and intralesional injections for ear keloids: Early results from a retrospective cohort study (CDA 2025) - "Only 20.0% (n = 9) of all patients reported experiencing side effects, consisting of pruritus (11.1%; n = 5), tenderness (4.4%; n = 2), pain (2.2%; n = 1), and mild atrophy (2.2%; n = 1). Conclusion Extralesional surgical shave excision followed by intralesional triamcinolone acetonide and onabotulinumtoxinA injections may represent a promising treatment option for ear keloids."

Retrospective data • Dermatology • Fibrosis • Pain • Pruritus

Vulvar Crohn Disease: A Case Report (CDA 2025) - "Management options for VCD may include topical corticosteroids, calcineurin inhibitors, metronidazole , systemic corticosteroids, sulfasalazine , azathioprine, TNFα inhibitors, IL-12/23 inhibitors, and surgical treatment...We continued her adalimumab and prescribed metronidazole 500mg BID. With minimal improvement after 2 months, the patient consented to triamcinolone acetonide 5mg/mL injections (ILTAC) preceded by the application of lidocaine 5% gel...Reports on ILTAC as a treatment modality for VCD are limited in the literature and remain absent from proposed treatment algorithms. Given the considerable improvement our patient experienced with ILTAC injections, it should be considered as a first-line treatment for VCD and for patients who fail other treatment options."

Case report • Clinical • Crohn's disease • Dermatology • Gastroenterology • Gastrointestinal Disorder • Genetic Disorders • Hidradenitis Suppurativa • Immunology • Inflammation • Inflammatory Bowel Disease • Pain • Pruritus • Psoriasis • IL12A