triamcinolone acetonide / Generic mfg. - LARVOL DELTA

Intravitreal triamcinolone acetonide therapy in serpiginous-like choroiditis. (PubMed, Indian J Ophthalmol) - "IVTA at a 2 mg dose appears effective in lesion resolution, while minimizing systemic therapy in SLC, with an acceptable safety profile and no paradoxical worsening. Larger prospective studies are needed to validate these findings."

Journal • Cataract • Ocular Inflammation • Ophthalmology • Uveitis

RegenOSF: Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis (clinicaltrials.gov) - P=N/A | N=40 | Not yet recruiting | Sponsor: Karachi Medical and Dental College

New trial • Fibrosis • Immunology

A technique of TA-assisted ILM peeling for myopic foveoschisis. (PubMed, BMC Surg) - P=N/A | "Due to the strong adhesion of the posterior cortical vitreous, the internal limiting membrane (ILM) is difficult to stain with ICG. In contrast, TA can adhere well to the vitreous cortex and remain on the macular surface in eyes with MF. TA-assisted FILMP is a feasible approach for ILM peeling in MF. Large-sample, prospective and randomized controlled trials are needed to confirm these findings."

Journal • Retinal Disorders

B12-KEN-TRAUM: Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic Treatment (clinicaltrials.gov) - P=N/A | N=76 | Recruiting | Sponsor: Hawraa Ali Abdullah | Not yet recruiting ➔ Recruiting

Enrollment open

Risk Factors and Effect of Sub-Tenon Triamcinolone on Cystoid Macular Edema After Descemet Membrane Endothelial Keratoplasty: Association and Risk Factor Analysis. (PubMed, Cornea) - "STTA was not significantly associated with a lower incidence of CME after DMEK. Shallow anterior chamber depth showed a trend toward association, and rebubbling was significantly associated, suggesting the need for careful postoperative evaluation."

Journal • Macular Edema • Ophthalmology • Transplantation

Corticosteroid infiltration in partial distal biceps ruptures. (PubMed, Clin Shoulder Elb) - "Infiltration with corticosteroids is a safe treatment option for patients with a partial tear of the distal biceps who failed progressive exercise therapy. Surgical reconstruction was avoided in 35% of patients following infiltration treatment. Level of evidence: IV."

Journal • Pain

Efficacy of Intra-articular Hyaluronic Acid and Triamcinolone Acetonide Combination Versus Hyaluronic Acid Alone in Knee Osteoarthritis. (PubMed, Cureus) - "The results from this study suggest a synergistic effect between hyaluronic acid and triamcinolone, thus making them a more efficacious treatment option compared to hyaluronic acid alone in the treatment of K & L grade 2 and 3 knee OA. The findings from this study were based on a 12-week follow-up, more studies are encouraged to validate the findings over a longer period."

Journal • Immunology • Orthopedics • Osteoarthritis • Pain • Rheumatology

Remote Sensing of Endogenous Pigmentation by Inducible Synthetic Circuits in Grasses. (PubMed, Plant Biotechnol J) - "We also test multiple ligands to overcome physical barriers to ligand uptake, identifying triamcinolone acetonide (TA) as a highly potent inducer of this system...This work demonstrates the use of inducible expression systems in monocots to manipulate endogenous pigmentation production for remote detection. Applying inducible anthocyanin production coupled with sensitive detection algorithms could enable crop plants to report on the status of field contamination or detect undesirable chemicals impacting agriculture, ushering in an era of agriculture-based sensor systems."

Journal

Phenol Neurolysis Versus Local Anesthetic Plus Steroid Genicular Nerve Block in Knee Osteoarthritis (clinicaltrials.gov) - P=N/A | N=42 | Active, not recruiting | Sponsor: Salim Sencar

New trial • Anesthesia • Immunology • Osteoarthritis • Pain • Rheumatology

Cataract surgery with IOL implantation in children with chronic anterior uveitis associated with juvenile idiopathic arthritis (JIA) or antinuclear antibody (ANA)-positive uveitis: mid-term results and predictors for outcome. (PubMed, Am J Ophthalmol) - "According to our observations, IOL implantation can be considered for children with JIA-associated or ANA-positive uveitis, on the condition that their uveitis is well controlled with DMARD therapy and the surgical technique is appropriate. The long-term course of the inflammatory disease determines the occurrence of intraocular complications related to inflammation and the visual outcome."

Biomarker • Journal • Cataract • Fibrosis • Glaucoma • Idiopathic Arthritis • Immunology • Inflammation • Macular Edema • Ocular Inflammation • Ophthalmology • Rheumatology • Uveitis

Comparison of the Efficacy of Conventional Radiofrequency to Intraarticular Steroid Injections for Advanced Hip Osteoarthritis: A Randomized Trial. (PubMed, Pain Physician) - "Conventional RF is more effective at treating the symptoms of advanced coxarthrosis than are intraarticular steroids, based on observations of the activity in the 3-month follow-up of patients with the condition."

Journal • Immunology • Osteoarthritis • Pain • Rheumatology

Optical Coherence Tomography (OCT) Biomarkers for Nonsurgical Management of Postvitrectomy Secondary Macular Holes With Intravitreal Triamcinolone Acetonide (1 mg/0.1 mL): A Case Report of Two Cases. (PubMed, Case Rep Ophthalmol Med) - "There have been reports on the closure of secondary macular holes with the intravitreal injection of triamcinolone acetonide, intravitreal bevacizumab, aflibercept, NSAID, and difluprednate. The identification of OCT biomarkers prior to vitrectomy can help in targeted use of nonsurgical treatment modalities in the management of secondary macular holes with the intravitreal injection of triamcinolone acetonide (1 mg/0.1 mL). Identification of OCT biomarkers can help in the nonsurgical management of secondary macular holes."

Biomarker • Journal • Macular Edema • Mood Disorders • Ophthalmology • Retinal Disorders

Efficacy of faricimab for recalcitrant multifactorial cystoid macular edema. (PubMed, Am J Ophthalmol Case Rep) - "This manuscript describes a case of recalcitrant postoperative cystoid macular edema (CME), confounded by a history of branch retinal vein occlusion (BRVO), in which faricimab resulted in resolution of CME after incomplete response to topical anti-inflammation drops, intravitreal aflibercept and bevacizumab, a corticosteroid intravitreal implant, grid laser therapy, and suprachoroidal triamcinolone acetonide (SCS-TA)...CME persisted for eight years despite treatment with topical anti-inflammatories, anti-VEGF injections, a dexamethasone intravitreal implant, grid laser therapy, and a SCS-TA injection...This case demonstrates the effectiveness of faricimab in treatment of CME resistant to other therapies and the importance of continued attempts at using new agents for chronic, recurrent CME. The unique benefits of new agents like faricimab, with both VEGF and Ang-2 inhibition, may be particularly helpful in mixed or inflammatory CME when other proven therapies have failed."

Journal • Age-related Macular Degeneration • Cardiovascular • Diabetic Macular Edema • Glaucoma • Inflammation • Macular Degeneration • Macular Edema • Ophthalmology • Retinal Disorders • Retinal Vein Occlusion • Wet Age-related Macular Degeneration

Retinal phlebitis complicated by punctate inner choroidopathy-like lesions: a case report. (PubMed, Am J Ophthalmol Case Rep) - "Treatment with oral prednisolone and sub-Tenon triamcinolone acetonide injections controlled the inflammation, and intravitreal aflibercept injections managed the CNV. At the two-year follow-up, the corrected visual acuity improved to 1.2. The distribution of lesions along the retinal veins suggests that this case represents a presentation of PIC-like lesions secondary to retinal phlebitis."

Journal • Inflammation • Ophthalmology • Retinal Disorders

Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA) (clinicaltrials.gov) - P2 | N=40 | Recruiting | Sponsor: Université du Québec à Trois-Rivières | Not yet recruiting ➔ Recruiting | Phase classification: PN/A ➔ P2

Enrollment open • Phase classification • Immunology • Osteoarthritis • Pain • Rheumatology

Potato Peel Extract Reduces MMP-9 Expression During Oral Mucosal Wound Healing in Rats. (PubMed, J Inflamm Res) - "Among the two concentrations, the 4% extract group showed a lower mean MMP-9 expression compared to the 6% group. Granola potato peel ethanol extract gel at a concentration of 4% was the most effective in reducing MMP-9 expression compared to the 6% extract and 0.1% triamcinolone acetonide during oral mucosal wound healing, highlighting its potential as a natural alternative to corticosteroids and contributing to innovation in pharmaceutical research."

Journal • Preclinical • MMP9

Suprachoroidal Triamcinolone Acetonide for the Treatment of Refractory Macular Edema Secondary to Non-Infectious Uveitis. (PubMed, Res Sq) - "The initial improvement in logMAR visual acuity and CST was less pronounced at follow-up visits at 6-7 months and 11-12 months. Conclusions This study demonstrates the safety of suprachoroidal TA and efficacy signals including improvement in visual acuity and ME at 3 months in patients with severe, refractory ME secondary to NIU."

Journal • Immunology • Macular Edema • Ocular Inflammation • Ophthalmology • Retinal Disorders • Uveitis

Functional gene abundance and metabolic pathways during defluorination of fluorinated glucocorticoids by Acinetobacter pittii C3 in natural waters under different seasonal temperatures. (PubMed, Environ Res) - "This study investigated the effects of seasonal temperature variations on the expression of defluorination functional genes and metabolic pathways during the degradation of the representative FGCs triamcinolone acetonide (TA) by the defluorinating strain Acinetobacter pittii C3...This work demonstrates intrinsic quantitative linkages among temperature, microbial physiology, gene abundance, and pollutant removal, supported by strong correlations (R > 0.8, Mantel test) between defluorination gene and efficiency. These findings offer new mechanistic insights and theoretical support for optimizing bioremediation strategies under seasonal conditions."

Journal

Betamethasone and Triamcinolone Acetonide Have Comparable Efficacy as Single Intra-Articular Injections in Knee Osteoarthritis: A Double-Blinded, Randomized Controlled Trial. (PubMed, J Bone Joint Surg Am) - "No significant differences were observed between IA betamethasone and triamcinolone acetonide with respect to VAS pain, functional scores, or performance-based outcomes at 6 months."

Journal • Immunology • Osteoarthritis • Pain • Rheumatology

Subconjunctival Triamcinolone Acetonide in the Treatment of Non-necrotizing, Non-infectious Anterior Scleritis. (PubMed, Cureus) - "STI provides effective local disease control and symptom relief in non-necrotizing, non-infectious anterior scleritis, while reducing systemic treatment burden. They appear to be a safe, cost-effective adjunct, though careful patient selection and monitoring for IOP elevation are essential."

Journal • Anesthesia • Cardiovascular • Cataract • Glaucoma • Inflammation • Ocular Inflammation • Ophthalmology • Pain • Scleritis

Pseudomyogenic Hemangioendothelioma with Novel NEDD9-FOSB Fusion Gene (ASDP 2025) - "Initially, the lesion was diagnosed as a dermatofibroma and treated with intralesional triamcinolone acetonide, but no improvement was seen...This specific genetic fusion, in addition to SERPINE1-FOSB and ACTB-FOSB have not been described in other soft-tissue neoplasms, making them distinct diagnostic markers for PMHE. The discovery of the NEDD9-FOSB fusion adds to the current genetic understanding of PMHE and presents a new variant that warrants further exploration as a potential therapeutic target."

Sarcoma • Soft Tissue Sarcoma • Solid Tumor • CD31 • CD34 • MLANA • NEDD9 • PECAM1 • SERPINE1

Evaluation of the Triamcinolone -Acetonide Therapy for the Treatment of the Medial Plica Syndrome (clinicaltrials.gov) - P=N/A | N=30 | Completed | Sponsor: Istituto Ortopedico Rizzoli | Active, not recruiting ➔ Completed

Trial completion

Efficacy of Single Intra-articular 2% Sodium Hyaluronate versus Corticosteroid Injection in Isolated Patellofemoral Osteoarthritis: A Double-Blind, Randomized Controlled Trial. (PubMed, J ISAKOS) - "Intra-articular HA and CS injections provide comparable pain reduction and functional score improvement at 6-month follow-up in patients with PFOA, with better pain relief in the first week for the CS group. Intra-articular HA may be an alternative to CS, with the equivalent results but without increasing the risk of chondrotoxicity and cartilage volume loss, especially in isolated PFOA patients whose tibiofemoral compartment cartilage is relatively preserved."

Journal • Immunology • Musculoskeletal Pain • Osteoarthritis • Pain • Rheumatology

Analytical and usability comparison of microsampling dried blood spot devices for glucocorticoid detection in sports using ultra-high-performance liquid chromatography-tandem mass spectrometry. (PubMed, Anal Chim Acta) - "In contrast, Card and Fan exhibited lower recoveries and higher variability, particularly for methylprednisolone and triamcinolone acetonide...These results highlight the importance of selecting appropriate DBS devices and optimizing protocols for glucocorticoid analysis. Further validation and longitudinal studies are warranted to support DBS implementation in routine anti-doping programs."

Clinical • Journal

Prophylactic adjuvant therapy for postoperative recurrence of urethral stricture: a narrative review. (PubMed, Transl Androl Urol) - "For the period from 2004 to 2025, we searched the terms "urethral stricture", "postoperative recurrence", "mitomycin C", "paclitaxel", "steroids", "pirfenidone", "hydrogel", and "biodegradable stents" in the PubMed, Embase, and Web of Science databases and conducted a narrative review...Steroids, particularly triamcinolone acetonide (TA), decrease recurrence when used postoperatively, including via steroid-coated or ointment-coated clean intermittent catheterization (CIC)...Postoperative adjuvant strategies-particularly PTX DCB and TA-based steroid-coated CIC-can further reduce recurrence in selected scenarios. Translation of MMC and TA into standardized, postoperative regimens and rigorously designed trials for PFD and smart delivery systems are priorities."

Journal • Review • Fibrosis • Immunology • Urology