BXT-110
/ BrainXell
- LARVOL DELTA
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November 15, 2025
BrainXell Showcases Pioneering iPSC Research and Promising In Vivo Data for BXT-110 for Parkinson's Disease at the 2025 Society for Neuroscience Annual Meeting
(PRNewswire)
- "The data demonstrates more than 75 percent FOXA2+/OTX2+ expression, over 60% TH+ neurons in vitro and greater than 60 percent graft survival in vivo. Functional efficacy in rodent model, demonstrated by a significant behavioral recovery within 12 weeks post transplantation with BXT-110, supporting BXT-110 as a robust candidate for disease-modifying therapy."
Preclinical • Parkinson's Disease
November 03, 2025
BrainXell Therapeutics Unveils Promising Preclinical Data Demonstrating Efficacy of BXT-110, an Autologous iPSC-Derived Neuronal Therapy, in Parkinson’s Disease
(PRNewswire)
- "The data presented highlights BrainXell Therapeutics' progress in developing a robust, reproducible, and scalable approach for BXT-110, an autologous source of midbrain dopaminergic progenitor (mDAPs) for PD....In vivo studies demonstrated significant graft survival and substantial functional recovery in a 6-OHDA rodent model, with efficacy observed as early as 12 weeks and sustained for up to six months post-transplantation."
Preclinical • Parkinson's Disease
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