Polygam S/D (human immune globulin intravenous) / Takeda - LARVOL DELTA

Meeting highlights from the Committee for Medicinal Products for Human Use (CHMP) 24-27 February 2025 (European Medicines Agency) - "The committee recommended granting a marketing authorisation for Deqsiga (human normal immunoglobulin), intended for replacement therapy in people with primary or secondary immunodeficiencies and immunomodulation in people with certain autoimmune diseases."

CHMP • Immunology • Primary Immunodeficiency

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma (clinicaltrials.gov) - P3 | N=53 | Completed | Sponsor: Children's Oncology Group | Active, not recruiting ➔ Completed | Trial completion date: Dec 2023 ➔ Dec 2022

Trial completion • Trial completion date • Ataxia • CNS Tumor • Movement Disorders • Neuroblastoma • Neuroendocrine Tumor • Oncology • Solid Tumor

Analysis of longitudinal multivariate outcome data from couples cohort studies: application to HPV transmission dynamics. (PubMed) - "The method can be used to identify risk factors associated with HPV transmission and persistence, estimate difference in risks between male-to-female and female-to-male HPV transmission, compare type-specific transmission risks within couples, and characterize the inter-type and intra-couple associations. Applying the method to HPV couple data collected in a Ugandan male circumcision (MC) trial, we assessed the effect of MC and the role of gender on risks of HPV transmission and persistence."

Journal • Biosimilar • Oncology

Perception and risk factors for cervical cancer among women in northern Ghana. (PubMed) - Ghana Med J - "Women's perception of personal risk for cervical cancer is lower than their actual risk based on the five behavioural risk factors assessed and a lack of knowledge of the personal factors for the disease."

Journal • Biosimilar • Cervical Cancer • Oncology

Distribution of Quantum Coherence in Multipartite Systems. (PubMed) - Phys Rev Lett - "In the case of the XXZ Heisenberg model, the coherence changes from a monogamous to a polygamous nature. This allows us to define the shareability of coherence, leading to monogamy relations for coherence."

Journal • Biosimilar

Does Awareness of Status and Risks of Human Immunodeficiency Virus Impact Risky Transmission Behavior Among Infected Adolescents? A Case Study of Clients Attending an Antiretroviral Therapy (ART) Clinic in Kano, Kano State, Nigeria. (PubMed) - Indian J Community Med - "Health ministries, development partners working in this field, and behavioral change communication experts should develop formidable strategies for addressing this menace. There is also a dire need for further research in this area."

Journal • Biosimilar • Gene Therapies

Population Dynamics and Life History of Euphorbia rosescens, a Perennial Herb Endemic to Florida Scrub. (PubMed) - PLoS One - "Although most plants survived fire by resprouting, fire decreased survival and had a short-term positive effect on floral production. Lack of fecundity and recruitment are concerns for this state-endangered species, but more information is needed on its breeding system and clonality to make specific management recommendations."

Journal • Biosimilar