rizatriptan ODT / Generic mfg. - LARVOL DELTA

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache (clinicaltrials.gov) - P4 | N=80 | Recruiting | Sponsor: Antonios Likourezos | Trial completion date: Dec 2026 ➔ Dec 2028 | Trial primary completion date: Dec 2026 ➔ Dec 2028

Trial completion date • Trial primary completion date • CNS Disorders • Migraine

Development and Evaluation of Rizatriptan Benzoate Orally Disintegrating Tablets for Migraine Treatment. (PubMed, Drug Dev Ind Pharm) - "A highly porous structure was clearly observed on the surface of ODTs. There was no interaction between RZT and excipients.ConclusionsAs a result, ODT formulation of RZT, used in the treatment of migraine, has been successfully developed."

Journal • CNS Disorders • Migraine • Pain

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache (clinicaltrials.gov) - P4 | N=80 | Recruiting | Sponsor: Antonios Likourezos | Not yet recruiting ➔ Recruiting

Enrollment open • CNS Disorders • Migraine • Pain

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache (clinicaltrials.gov) - P4 | N=80 | Not yet recruiting | Sponsor: Antonios Likourezos

New P4 trial • CNS Disorders • Migraine • Pain

Drugs for the acute treatment of migraine in children and adolescents. (PubMed) - Cochrane Database Syst Rev - "Low quality evidence from two small trials shows that ibuprofen appears to improve pain freedom for the acute treatment of children with migraine. We have only limited information on adverse events associated with ibuprofen in the trials included in this review. Triptans as a class are also effective at providing pain freedom in children and adolescents but are associated with higher rates of minor adverse events. Sumatriptan plus naproxen sodium is also effective in treating adolescents with migraine."

Journal • Review • Biosimilar • Migraine • Pain

Unichem Laboratories receives US FDA approval for migraine drug (Business Standard) - "Unichem Laboratories Limited has received ANDA approval from the US Food and Drug Administration (FDA) for rizatriptan benzoate ODT 5 mg & 10 mg and rizatriptan benzoate tablets 5 mg & 10 mg. Rizatriptan benzoate ODT and rizatriptan benzoate tablets are therapeutically equivalent to Merck & Co’s Maxalt MLT tablets and Maxalt tablets, respectively."

ANDA • Migraine