remifentanil / Generic mfg. - LARVOL DELTA

Electroencephalogram-guided anesthesia and postoperative anxiety and depression in elderly gastric cancer patients with sleep disorders. (PubMed, World J Psychiatry) - "For elderly gastric cancer patients with preoperative sleep disorders, individualized anesthesia guided by EEG monitoring significantly reduces postoperative anxiety and depression symptoms, lowers postoperative delirium risk, shortens hospital stay, and improves postoperative quality of life. The stability of anesthesia depth is closely associated with postoperative mental health outcomes, providing new clinical evidence and individualized strategies for perioperative management of high-risk elderly patients."

Journal • Anesthesia • CNS Disorders • Depression • Gastric Cancer • Mood Disorders • Oncology • Pain • Psychiatry • Sleep Disorder • Solid Tumor

From fast track to enhanced recovery after Cardiac surgery: 15 years of experience with the Leipzig concept in a specialized post-anesthesia care unit. (PubMed, J Clin Anesth) - "This study presents the largest collection of consecutive ERACS patients ever collected and demonstrates the safety and efficacy of ERACS management with a specialized PACU, highlighting the benefits of continuous protocol optimization."

Journal • Anesthesia • Cardiovascular • CNS Disorders

Perioperative management of a patient with Kennedy disease undergoing knee replacement: A case report (PubMed, Beijing Da Xue Xue Bao Yi Xue Ban) - "After sufficient preoperative consultation and evaluation, femoral nerve block was performed with 0.25% ropivacaine under guidance with ultrasound and nerve stimulator, followed by induction of general anesthesia with sufentanil, propofol, and etomidate...During the operation, propofol and remifentanil were used for total intravenous anesthesia...A postoperative analgesia combination of nerve block and oral nonsteroidal analgesics was performed, and emergency pain rescue with pethidine was administered if necessary. The analgesic effect was satisfactory. The patient was safely discharged in the end and recovered well."

Journal • Anesthesia • Cardiovascular • Coronary Artery Disease • Genetic Disorders • Heart Failure • Infectious Disease • Muscular Atrophy • Musculoskeletal Diseases • Orthopedics • Pain • Respiratory Diseases

Low-Dose Rocuronium with Sugammadex Reversal in Bronchoscopy: A Randomized, Double-Blind, Controlled Trial (ChiCTR) - P=N/A | N=60 | Not yet recruiting | Sponsor: Jiangsu Taizhou People's Hospital; Jiangsu Taizhou People's Hospital

New trial

A Heart Under Stress: Anaesthetic Strategy for a Pregnant Patient With Long QT Syndrome. (PubMed, Cureus) - "Total intravenous anaesthesia with propofol and remifentanil was used, alongside strict electrolyte optimisation, sympathetic control, and continuous advanced monitoring. Careful perioperative planning and appropriate monitoring can enable the safe use of general anaesthesia for caesarean section in selected women with LQTS1."

Journal • Anesthesia • Cardiovascular • Obstetrics

The Effect of Sevoflurane and Desflurane on Clara Cell Protein in the Lung in Liver Transplant Donors. (PubMed, Niger J Clin Pract) - "When used at clinical doses, sevoflurane and desflurane had no adverse effects on CC16, an important marker of acute airway injury, in healthy lungs. We found that sevoflurane decreased the CC16' level more than desflurane."

Clinical • Journal • Anesthesia • Inflammation • Pulmonary Disease • Respiratory Diseases • Transplantation

Pain management for placement of peripherally inserted central catheters in neonates: A systematic review and meta-analysis. (PubMed, Paediatr Child Health) - "The interventions included intravenous opioids (morphine, remifentanil), topical anesthetics (tetracaine) and intravenous acetaminophen. Topical anesthetics and acetaminophen were not demonstrated to be effective. Further research is necessary to guide healthcare professionals in implementing optimal pain management for this procedure."

Journal • Retrospective data • Anesthesia • Pain

Effectiveness of Bleeding Control Methods in Rhinoplasty: A Systematic Review and Meta-Analysis. (PubMed, Arch Plast Surg) - "The bleeding control methods evaluated included tranexamic acid (TXA), desmopressin, steroids, magnesium sulfate, clonidine, remifentanil, and patient positioning (reverse Trendelenburg position). However, further studies with larger sample sizes and standardized designs are recommended for magnesium sulfate, clonidine, and remifentanil methods. Level of Evidence I."

Journal • Retrospective data • Aesthetic Medicine

SPROUT-2: Continuous Versus 1-min Oscillometric Arterial BP Monitoring (clinicaltrials.gov) - P=N/A | N=258 | Completed | Sponsor: Seoul National University Hospital | Recruiting ➔ Completed | Trial completion date: Nov 2025 ➔ Aug 2025 | Trial primary completion date: Nov 2025 ➔ Aug 2025

Head-to-Head • Trial completion • Trial completion date • Trial primary completion date • Anesthesia • Hypotension

Effect of Non-Opioid Anesthetic Strategies on Postoperative Recovery Quality Following Knee Arthroplasty (ChiCTR) - P=N/A | N=98 | Completed | Sponsor: Hebei Medical University Third Hospital; Hebei Medical University Third Hospital | Not yet recruiting ➔ Completed

Trial completion • Anesthesia • Orthopedics

The effect of ciprofol combined with remifentanil on the postoperative recovery quality in patients undergoing cervical spine surgery (ChiCTR) - P1 | N=208 | Recruiting | Sponsor: The First Affiliated Hospital of University of Science and Technology of China; The First Affiliated Hospital of University of Science and Technology | Not yet recruiting ➔ Recruiting | N=102 ➔ 208

Enrollment change • Enrollment open • Orthopedics

Effects of different sedative drug administration methods on sedative effect and postoperative agitation in children (ChiCTR) - P=N/A | N=783 | Recruiting | Sponsor: Zigong Fourth People's Hospital(Zigong First-aid Center); Zigong Fourth People's Hospital(Zigong First-aid Center) | Not yet recruiting ➔ Recruiting | Initiation date: Jul 2025 ➔ Nov 2025

Enrollment open • Trial initiation date • Anesthesia • Gastrointestinal Disorder • Pain

A Phase II, Multicenter, Randomized, single-Blind, Dose exploration, Positive Comparator Study to Evaluate the Efficacy and Safety of Tegileridine Fumarate lnjection for prolonged mechanical ventilation abirritation in the intensive care unit (ICU) (ChiCTR) - P2 | N=120 | Not yet recruiting | Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University o

New P2 trial • Critical care

Comparing Two Anesthesia Methods: Which Helps Elderly Colon Surgery Patients Recover Better? (ChiCTR) - P4 | N=120 | Not yet recruiting | Sponsor: People's Hospital of Jianyang City; People's Hospital of Jianyang City

New P4 trial • Anesthesia • Colon Cancer • Colorectal Cancer • Oncology • Rectal Cancer • Solid Tumor

Study on the application value of oxalidine fumarate injection for analgesia in emergency pre-hospital patients with severe trauma (ChiCTR) - P4 | N=80 | Recruiting | Sponsor: Fushun County People's Hospital; Fushun County People's Hospital

New P4 trial • Mood Disorders

A randomized controlled study of ciprofol (HSK3486) and propofol for short urological operations in elderly patients (ChiCTR) - P4 | N=94 | Not yet recruiting | Sponsor: Zhuzhou Central Hospital (Affiliated Zhuzhou Hospital of Xiangya School of Medicine, Central South University); Zhuzhou Central Hospital (Affiliated Z

New P4 trial • Urology

Research on the use of remazolam compound rifentanyl sober sedation for gastroscopy examination of obesity (ChiCTR) - P4 | N=140 | Recruiting | Sponsor: Zigong Fourth People's Hospital; Zigong Fourth People's Hospital

New P4 trial • Anesthesia • Genetic Disorders • Obesity

Comparing the Efficacy and Safety of Propofol and Remimazolam during Rapid Sequential Intubation Induction: A Prospective, Randomized Controlled, Non-Inferiority Trial (ChiCTR) - P4 | N=180 | Recruiting | Sponsor: Xiamen Hospital of Zhongshan Hospital Affiliated to Fudan University; Xiamen Hospital of Zhongshan Hospital Affiliated to Fudan University

New P4 trial • Anesthesia

Remimazolam versus Midazolam for Respiratory Mechanics in ARDS Patients Requiring Mechanical Ventilation: A Multicenter Randomized Controlled Trial (ChiCTR) - P4 | N=334 | Recruiting | Sponsor: Affiliated Hospital of Guangdong Medical University; Affiliated Hospital of Guangdong Medical University

New P4 trial • Acute Lung Injury • Acute Respiratory Distress Syndrome • Pulmonary Disease • Respiratory Diseases

Comparison of the safety of remazolam besylate and midazolam combined with sufentanil in painless fiberoptic bronchoscopy (ChiCTR) - P4 | N=82 | Recruiting | Sponsor: Ankang Hospital of Traditional Chinese Medicine; Ankang Hospital of Traditional Chinese Medicine

New P4 trial • Pain

Hemodynamic Effects (CI/SVR) of Ciprofol vs. Propofol during Anesthesia Induction in Older Orthopedic Patients: A Randomized Controlled Study (ChiCTR) - P4 | N=130 | Not yet recruiting | Sponsor: The First Affiliated Hospital of USTC (Anhui Provincial Hospital); The First Affiliated Hospital of USTC (Anhui Provincial Hospital)

New P4 trial • Anesthesia • Orthopedics

A Study on the Feasibility of Remimazolam for Day Surgery (ChiCTR) - P4 | N=100 | Not yet recruiting | Sponsor: ZhangZhou Municipal Hospital of Fujian province; ZhangZhou Municipal Hospital of Fujian province

New P4 trial • Anesthesia • Gastroenterology

The Effects of Propofol and Cipropofol on Perioperative Neurocognitive Disorders in Elderly Patients (ChiCTR) - P4 | N=134 | Not yet recruiting | Sponsor: Inner Mongolia Medical University Affiliated Hospital; Inner Mongolia Medical University Affiliated Hospital

New P4 trial • CNS Disorders • Cognitive Disorders • Developmental Disorders

The Effect of Remimazolam on Somatosensory and Motor Evoked Potentials during Spinal Surgery: A Randomized Controlled Study (ChiCTR) - P4 | N=142 | Recruiting | Sponsor: Beijing Tiantan Hospital, Capital Medical University, Beijing, China; Beijing Tiantan Hospital Affiliated to Capital Medical University

New P4 trial

Efficacy and Safety of Anrikefon Injection for Postoperative Analgesia in Adults Undergoing Cholecystectomy: A Prospective, Randomized, Controlled, Non-inferiority Trial (ChiCTR) - P4 | N=220 | Not yet recruiting | Sponsor: The Second Affiliated Hospital of Nanjing Medical University; The Second Affiliated Hospital of Nanjing Medical University

New P4 trial