LTI-002
/ Leukogene Therap
- LARVOL DELTA
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March 18, 2026
MHC class II targeted immunotherapy in the treatment of pancreatic cancer
(AACR 2026)
- "We observed synergy in combination with PDAC standard of care agents like gemcitabine, RAS(ON) inhibitors, and anti-PD1 immunotherapy. This study demonstrates the therapeutic potential of targeting MHCII to stimulate anti-PDAC immunity."
IO biomarker • Tumor mutational burden • Microsatellite Instability • Oncology • Pancreatic Cancer • Pancreatic Ductal Adenocarcinoma • Solid Tumor • CD4 • HLA-DRB1 • MSI • MSLN • TMB
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