NVX-207
/ Novelix
- LARVOL DELTA
Home
Next
Prev
1 to 4
Of
4
Go to page
1
May 17, 2024
Potent drug delivery enhancement of betulinic acid and NVX-207 into equine skin in vitro - a comparison between a novel oxygen flow-assisted transdermal application device and microemulsion gels.
(PubMed, BMC Vet Res)
- "All tested substances showed promising results. Additionally, OFA administration showed a significant accumulation of NVX-207 after 30 min and 24 h of incubation. Further in vivo trials with OFA application are recommended."
Journal • Preclinical • Melanoma • Oncology • Solid Tumor
November 29, 2021
Effects of Topically Applied Betulinic Acid and NVX-207 on Melanocytic Tumors in 18 Horses.
(PubMed, Animals (Basel))
- "The findings must be regarded as preliminary due to the limited group size and need to be replicated in a larger cohort with modified pharmaceutical test formulations. Accordingly, the treatment protocol cannot yet be recommended in its current form."
Clinical • Journal • Cutaneous Melanoma • Melanoma • Oncology • Skin Cancer • Solid Tumor
November 06, 2020
In vitro assessment of triterpenoids NVX-207 and betulinyl-bis-sulfamate as a topical treatment for equine skin cancer.
(PubMed, PLoS One)
- "Even though data obtained in vitro are auspicious, the results are not unconditionally applicable to the clinical situation. Consequently, in vivo studies are required to address the antitumoral effects of topically applied NVX-207 in ES and EMM patients."
Journal • Preclinical • Genetic Disorders • Melanoma • Oncology • Skin Cancer • Solid Tumor
August 28, 2020
Concentration profiles and safety of topically applied betulinic acid and NVX-207 in eight healthy horses-A randomized, blinded, placebo-controlled, crossover pilot study.
(PubMed, J Vet Pharmacol Ther)
- "Good systemic tolerability and only mild local adverse effects were observed in all three groups. This study substantiates the topical application of BA and NVX-207 in further clinical trials with horses suffering from EMM; however, penetration and permeation of the compounds may be altered in skin affected by tumors."
Clinical • Journal • Melanoma • Oncology • Solid Tumor
1 to 4
Of
4
Go to page
1