KQB198 / Kumquat Biosci - LARVOL DELTA

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies (clinicaltrials.gov) - P1 | N=92 | Active, not recruiting | Sponsor: Kumquat Biosciences Inc. | Trial primary completion date: Jul 2026 ➔ Dec 2026

Monotherapy • Trial primary completion date • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • EGFR • NF1 • PTPN11

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies (clinicaltrials.gov) - P1 | N=92 | Active, not recruiting | Sponsor: Kumquat Biosciences Inc. | Recruiting ➔ Active, not recruiting

Enrollment closed • Monotherapy • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • EGFR • NF1 • PTPN11

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (clinicaltrials.gov) - P2 | N=46 | Recruiting | Sponsor: Kumquat Biosciences Inc. | Not yet recruiting ➔ Recruiting

Enrollment open • Gastrointestinal Cancer • Gastrointestinal Stromal Tumor • Oncology • Sarcoma • Solid Tumor • KIT

KQB198-102: A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Hematologic Malignancies (clinicaltrials.gov) - P1 | N=13 | Active, not recruiting | Sponsor: Kumquat Biosciences Inc. | Recruiting ➔ Active, not recruiting | N=122 ➔ 13 | Trial completion date: Feb 2028 ➔ Mar 2027 | Trial primary completion date: Aug 2027 ➔ Mar 2027

Enrollment change • Enrollment closed • Monotherapy • Trial completion date • Trial primary completion date • Hematological Malignancies • Oncology

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (clinicaltrials.gov) - P2 | N=46 | Not yet recruiting | Sponsor: Kumquat Biosciences Inc.

New P2 trial • Gastrointestinal Cancer • Gastrointestinal Stromal Tumor • Oncology • Sarcoma • Solid Tumor • KIT

A Study to Investigate the Safety and Efficacy of KQB198 As Monotherapy and in Combination in Participants with Advanced Hematologic Malignancies (clinicaltrials.gov) - P1 | N=122 | Recruiting | Sponsor: Kumquat Biosciences Inc.

Combination therapy • Metastases • Monotherapy • New P1 trial • Hematological Disorders • Hematological Malignancies • Oncology • ABL1 • BCR

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies (clinicaltrials.gov) - P1 | N=100 | Recruiting | Sponsor: Kumquat Biosciences Inc.

Combination therapy • Metastases • Monotherapy • New P1 trial • Oncology • Solid Tumor