HinsBet (human insulin) / Adocia - LARVOL DELTA

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P2/3 | N=20 | Terminated | Sponsor: Massachusetts General Hospital | N=45 ➔ 20 | Enrolling by invitation ➔ Terminated; Devices are not available

Enrollment change • Trial termination • Diabetes • Metabolic Disorders • Type 1 Diabetes Mellitus

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P2/3; N=45; Enrolling by invitation; Sponsor: Massachusetts General Hospital; Trial completion date: Dec 2020 ➔ Dec 2021; Trial primary completion date: Dec 2020 ➔ Dec 2021

Clinical • Trial completion date • Trial primary completion date • Diabetes • Metabolic Disorders • Type 1 Diabetes Mellitus

Hard time to be parents? Sea urchin fishery shifts potential reproductive contribution of population onto the shoulders of the young adults. (PubMed) - PeerJ - "Overall, the lack of the commercial-size class in the high-pressure zone does not seem to be very alarming for the self-supporting capacity of the population, and the reproductive potential contribution seems to depend more on the total density of fertile sea urchins than on their size. However, since population survival in the high-pressure zone is supported by the high density of undersized sea urchins between 30 and 50 mm, management measures should be addressed to maintain these sizes and to shed light on the source of the larval supply."

Journal • Biosimilar

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P2/3; N=45; Enrolling by invitation; Sponsor: Massachusetts General Hospital; Trial primary completion date: Dec 2019 ➔ Dec 2020

Clinical • Trial primary completion date

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P2/3; N=45; Enrolling by invitation; Sponsor: Massachusetts General Hospital; Recruiting ➔ Enrolling by invitation

Clinical • Enrollment status

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P2/3; N=45; Recruiting; Sponsor: Massachusetts General Hospital; Not yet recruiting ➔ Recruiting; Phase classification: PN/A ➔ P2/3; N=20 ➔ 45

Clinical • Enrollment change • Enrollment open • Phase classification

Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas (clinicaltrials.gov) - P=N/A; N=20; Not yet recruiting; Sponsor: Massachusetts General Hospital; Trial completion date: Dec 2019 ➔ Dec 2020

Clinical • Trial completion date