Filatil (filgrastim biosimilar) / Probiomed - LARVOL DELTA

Effectiveness of Innovator Pegfilgrastim (Neulastim®), Generic Pegfilgrastim (Linkix®) and Filgrastim for Engraftment after Auto-HSCT in an Outpatient Setting. (TCT-ASTCT-CIBMTR 2023) - P2 | "HL and NHL patients received a conditioning regimen with bendamustine (180mg/m 2 /day/2days) and melphalan (140mg/m 2 /1day). Time to neutrophil and platelet engraftment by treatment arm (Neulastim®, Linkix®, y filgrastim) Conclusion In patients with lymphoma and multiple myeloma receiving auto-HSCT, generic pegfilgrastim (Linkix®) produced a similar neutrophil and platelet engraftment time to patent pegfilgrastim (Neulastim®). The use of pegfilgrastim produces a faster time to neutrophil and platelet engraftment compared to filgrastim."

Clinical • Bone Marrow Transplantation • Febrile Neutropenia • Hematological Disorders • Hematological Malignancies • Lymphoma • Multiple Myeloma • Musculoskeletal Pain • Neutropenia • Non-Hodgkin’s Lymphoma • Oncology • Pain • Transplantation

Efficacy of three filgrastim-intended copies for hematopoietic stem cell mobilization in healthy adult and pediatric donors in Mexico. (PubMed, J Clin Apher) - "In conclusion, three FICs available in Mexico were efficacious and without immediate severe adverse effects, resulting in significant cost savings. Evaluation of immunogenicity and establishment of a pharmacovigilance program with the use of FICs is warranted."

Clinical • Journal