GSK3039294 / GSK - LARVOL DELTA

Identification, preclinical profile and clinical proof of concept of an orally bio-available pro-drug of miridesap. (PubMed, Br J Pharmacol) - "Using a preclinical screening cascade, we identified a pro-drug for a palindromic molecule with unique pharmacology (miridesap). The pro-drug depleted circulating SAP with a time course and extent similar to that of parenterally-administered miridesap."

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