ropivacaine liposomal sustained release (HR18034) / Jiangsu Hengrui Pharma - LARVOL DELTA

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management in TKA (clinicaltrials.gov) - P2 | N=15 | Terminated | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | N=120 ➔ 15 | Trial completion date: Apr 2025 ➔ Oct 2024 | Recruiting ➔ Terminated; Sponsor's R&D Strategy adjusted

Enrollment change • Trial completion date • Trial termination • Orthopedics • Pain

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management in TKA (clinicaltrials.gov) - P2 | N=120 | Recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Not yet recruiting ➔ Recruiting

Enrollment open • Orthopedics • Pain

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management in TKA (clinicaltrials.gov) - P2 | N=120 | Not yet recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.

New P2 trial • Orthopedics • Pain

Evaluating the efficacy and safety of perianal injection of liposomal ropivacaine HR18034 for postoperative analgesia following hemorrhoidectomy: A multicenter, randomized, double-blind, controlled phase II clinical trial. (PubMed, J Clin Anesth) - "HR 18034 380 mg showed superior analgesic efficacy and equivalent safety compared to ropivacaine 75 mg after hemorrhoidectomy, thus preliminarily determined as minimum effective dose."

Clinical • Journal • P2 data • Anesthesia • Gastroenterology • Pain

A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy (clinicaltrials.gov) - P3 | N=294 | Completed | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Active, not recruiting ➔ Completed

Trial completion • Gastroenterology • Pain

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management (clinicaltrials.gov) - P2 | N=89 | Active, not recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Recruiting ➔ Active, not recruiting | Trial completion date: Jun 2023 ➔ Dec 2024 | Trial primary completion date: Jun 2023 ➔ Dec 2024

Enrollment closed • Trial completion date • Trial primary completion date • Orthopedics • Pain

A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy (clinicaltrials.gov) - P3 | N=294 | Active, not recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Recruiting ➔ Active, not recruiting

Enrollment closed • Gastroenterology • Pain

A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy (clinicaltrials.gov) - P3 | N=294 | Recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Not yet recruiting ➔ Recruiting

Enrollment open • Gastroenterology • Pain

A Trial of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy. (clinicaltrials.gov) - P2 | N=86 | Completed | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Not yet recruiting ➔ Completed | Trial completion date: Apr 2023 ➔ Oct 2022 | Trial primary completion date: Apr 2023 ➔ Oct 2022

Trial completion • Trial completion date • Trial primary completion date • Gastroenterology • Pain

Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management (clinicaltrials.gov) - P2 | N=96 | Recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Not yet recruiting ➔ Recruiting

Enrollment open • Pain

A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy (clinicaltrials.gov) - P3 | N=294 | Not yet recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.

New P3 trial • Gastroenterology • Pain

Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management (clinicaltrials.gov) - P2 | N=96 | Not yet recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.

New P2 trial • Pain

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management (clinicaltrials.gov) - P2 | N=96 | Recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd. | Not yet recruiting ➔ Recruiting

Enrollment open • Orthopedics • Pain

Phase Ⅱ Study of Adductor Canal Block With HR18034 for Postsurgical Pain Management (clinicaltrials.gov) - P2 | N=96 | Not yet recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.

New P2 trial • Orthopedics • Pain

A Trial of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy. (clinicaltrials.gov) - P2 | N=84 | Not yet recruiting | Sponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.

New P2 trial • Gastroenterology • Pain

A Trial of HR18034 in Inguinal Hernia Repair (clinicaltrials.gov) - P1; N=64; Recruiting; Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Clinical • New P1 trial • Gastroenterology • Pain