OC201/OC202e / Oncocross - LARVOL DELTA

OC201 and OC202e, an AI-driven drug combination, enhance the susceptibility of pancreatic cancer to FOLFIRINOX by modulating HIF-1α (AACR 2026) - "The AI-derived OC201/OC202e combination enhances sensitivity to FOLFIRINOX and suppresses metastasis by targeting HIF-1α and the EMT-stemness axis. Reductions in clonogenicity and resistance-related markers highlight its potential as an adjuvant to standard chemotherapy and underscore the promise of AI-guided strategies for developing synergistic therapeutic combinations."

Hepatocellular Cancer • Oncology • Pancreatic Cancer • Solid Tumor • CD44 • HIF1A