SCLnow 19 / Sclnow Biotech - LARVOL DELTA

SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc Degeneration (clinicaltrials.gov) - P1 | N=20 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Jun 2026 ➔ Dec 2026 | Trial primary completion date: Dec 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • Musculoskeletal Diseases

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia (clinicaltrials.gov) - P2 | N=45 | Not yet recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial primary completion date: Dec 2025 ➔ Jun 2026

Trial primary completion date • Ataxia • Movement Disorders

The Safety/Efficacy of hUC Mesenchymal Stem Cells（19#iSCLife®-OA） Therapy for Patients With Osteoarthritis (clinicaltrials.gov) - P2 | N=60 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • Immunology • Osteoarthritis • Pain • Rheumatology

hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis (clinicaltrials.gov) - P1 | N=20 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Dec 2025

Trial completion date • Trial primary completion date • Fibrosis • Hepatitis B • Immunology • Infectious Disease • Inflammation

hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility (clinicaltrials.gov) - P1 | N=25 | Completed | Sponsor: Sclnow Biotechnology Co., Ltd. | Recruiting ➔ Completed

Trial completion • Infertility • Sexual Disorders

hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility (clinicaltrials.gov) - P1 | N=24 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Apr 2025 ➔ Jun 2026 | Trial primary completion date: Mar 2025 ➔ Dec 2025

Trial completion date • Trial primary completion date • Infertility • Sexual Disorders

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia (clinicaltrials.gov) - P2 | N=45 | Not yet recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Dec 2025

Trial completion date • Trial primary completion date • Ataxia • Movement Disorders

The Safety/Efficacy of hUC Mesenchymal Stem Cells（19#iSCLife®-OA） Therapy for Patients With Osteoarthritis (clinicaltrials.gov) - P2 | N=60 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Jun 2025 ➔ Dec 2025 | Trial primary completion date: Dec 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • Immunology • Osteoarthritis • Pain • Rheumatology

The Safety and Efficiency Study of Mesenchymal Stem Cell (19#iSCLife®-POI) in Premature Ovarian Insufficiency (clinicaltrials.gov) - P2 | N=12 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Jun 2025 ➔ Jun 2026 | Trial primary completion date: Dec 2024 ➔ Dec 2025

Trial completion date • Trial primary completion date • Women's Health

Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS) (clinicaltrials.gov) - P1/2 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • Hematological Malignancies • Myelodysplastic Syndrome • Oncology

The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction (clinicaltrials.gov) - P1 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • CNS Disorders

The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH) (clinicaltrials.gov) - P1/2 | N=30 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date

The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF) (clinicaltrials.gov) - P1/2 | N=60 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • Cardiovascular • Congestive Heart Failure • Heart Failure

Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. (clinicaltrials.gov) - P1/2 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Dec 2026 | Trial primary completion date: Jun 2025 ➔ Jun 2026

Trial completion date • Trial primary completion date • CNS Disorders

SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc Degeneration (clinicaltrials.gov) - P1 | N=20 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2025 ➔ Jun 2026 | Initiation date: Oct 2024 ➔ Jun 2025 | Recruiting ➔ Suspended | Trial primary completion date: Jun 2025 ➔ Dec 2025

Trial completion date • Trial initiation date • Trial primary completion date • Trial suspension • Musculoskeletal Diseases

SCLife®-LDD hUC-MSCs Injection Therapy for Patients With Lumbar Intervertebral Disc Degeneration (clinicaltrials.gov) - P1 | N=20 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd.

New P1 trial • Musculoskeletal Diseases

hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis (clinicaltrials.gov) - P1 | N=20 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • Fibrosis • Hepatitis B • Hepatology • Immunology • Infectious Disease • Inflammation

The Safety and Efficiency Study of Mesenchymal Stem Cell (19#iSCLife®-POI) in Premature Ovarian Insufficiency (clinicaltrials.gov) - P2 | N=12 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Jun 2025 | Trial primary completion date: Dec 2023 ➔ Dec 2024

Trial completion date • Trial primary completion date • Women's Health

Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period. (clinicaltrials.gov) - P1/2 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • CNS Disorders

The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction (clinicaltrials.gov) - P1 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • CNS Disorders

hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis (clinicaltrials.gov) - P1 | N=20 | Recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Jun 2024 ➔ Dec 2024 | Trial primary completion date: Dec 2023 ➔ Jun 2024

Trial completion date • Trial primary completion date • Fibrosis • Hepatitis B • Hepatology • Immunology • Infectious Disease • Inflammation

The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF) (clinicaltrials.gov) - P1/2 | N=60 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • Cardiovascular • Congestive Heart Failure • Heart Failure

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia (clinicaltrials.gov) - P2 | N=45 | Not yet recruiting | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • Ataxia • Movement Disorders

The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH) (clinicaltrials.gov) - P1/2 | N=30 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date

Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS) (clinicaltrials.gov) - P1/2 | N=40 | Suspended | Sponsor: Sclnow Biotechnology Co., Ltd. | Trial completion date: Dec 2024 ➔ Dec 2025 | Trial primary completion date: Jun 2024 ➔ Jun 2025

Trial completion date • Trial primary completion date • Hematological Malignancies • Myelodysplastic Syndrome • Oncology