177Lu-NYM096
/ Peking Union Medical College, Norroy Biosci
- LARVOL DELTA
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January 01, 2026
NYCRRLT: 68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC
(clinicaltrials.gov)
- P1 | N=20 | Suspended | Sponsor: Peking Union Medical College Hospital | Recruiting ➔ Suspended
Trial suspension • Clear Cell Renal Cell Carcinoma • Genito-urinary Cancer • Oncology • Renal Cell Carcinoma • Solid Tumor
June 13, 2025
Very first experience with 68Ga/177Lu-NYM096 in patients with metastatic clear cell renal cell carcinoma
(SNMMI 2025)
- P1 | "Purpose/Background: NYM096 is a new-generation carbonic anhydrase 9 (CA9) targeting small molecule that can be labeled with both 68Ga and 177Lu. One patient with metastatic ccRCC, aged 61 years, was enrolled. The patient had progressive disease after 2 lines of treatment (1st line, axitinib plus pembrolizumab, 2nd line, lenvatinib plus pembrolizumab). 68Ga-NYM096 PET/CT (Figure 1) demonstrated multiple CA9-positive metastases involving lung, pleural, LN, bone, soft tissue, and thyroid."
Clinical • IO biomarker • Metastases • Clear Cell Renal Cell Carcinoma • Genito-urinary Cancer • Oncology • Solid Tumor • CA9
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