nepafenac PPDS (N-PPDS) / Mati Therap - LARVOL DELTA

Reply to comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery. (PubMed, J Cataract Refract Surg) - No abstract available

Clinical • Journal • Cataract • Immunology • Inflammation • Ocular Inflammation • Ophthalmology • Pain

Comment on: Safety and efficacy of a nepafenac punctal plug delivery system in controlling postoperative ocular pain and inflammation after cataract surgery. (PubMed, J Cataract Refract Surg) - No abstract available

Clinical • Journal • Cataract • Immunology • Inflammation • Ocular Inflammation • Ophthalmology • Pain

Safety and Efficacy of Nepafenac Punctal Plug Delivery System in Controlling Postoperative Ocular Pain and Inflammation following Cataract Surgery. (PubMed, J Cataract Refract Surg) - "The N-PPDS was safe and effective for the management of ocular pain and inflammation following cataract surgery."

Clinical • Journal • Cataract • Immunology • Inflammation • Ocular Inflammation • Ophthalmology • Pain

Novel delivery system shows positive performance in phase II trial (Ophthalmology Times) - P2, N=63; NCT03496467; Sponsor: Mati Therapeutics Inc.; "'Inflammation is common following cataract surgery, and it can lead to serious complications if left untreated. Results of the ESCRS prospective PREMED study showed that NSAIDs were more important than corticosteroids for reducing the risk of CME,' said Dr. Donnenfeld....'It demonstrated unprecedented efficacy in reducing pain and inflammation after cataract surgery in the phase II study. If the outcomes are confirmed in phase III trials, the nepafenac PPDS may effectively replace topical NSAID drops in cataract surgery.'"

Media quote • P2 data