SGR-5573 / Schrodinger - LARVOL DELTA

SGR-5573 is a potent, selective, brain-penetrant inhibitor of osimertinib-resistant EGFR variants (ESMO 2025) - "Given its strong activity against EGFR mutants with the C797S resistance mutation and the significant unmet medical need in this patient population, this preclinical data package supports investigation of SGR-5573 in the clinic. Legal entity responsible for the study Schrodinger Inc."

Brain Cancer • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • EGFR