Nexterone (captisol enabled amiodarone) / Ligand, Baxter Healthcare - LARVOL DELTA

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer (clinicaltrials.gov) - P2 | N=90 | Recruiting | Sponsor: OHSU Knight Cancer Institute | Trial completion date: Aug 2025 ➔ Aug 2026 | Trial primary completion date: Aug 2025 ➔ Aug 2026

Trial completion date • Trial primary completion date • Atrial Fibrillation • Cardiovascular • Esophageal Cancer • Gastrointestinal Cancer • Oncology

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer (clinicaltrials.gov) - P2 | N=90 | Recruiting | Sponsor: OHSU Knight Cancer Institute | Not yet recruiting ➔ Recruiting

Enrollment open • Atrial Fibrillation • Cardiovascular • Esophageal Cancer • Gastrointestinal Cancer • Oncology

AAA: Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study (clinicaltrials.gov) - P4 | N=42 | Recruiting | Sponsor: University of Calgary | Trial completion date: Dec 2026 ➔ Dec 2027 | Trial primary completion date: Dec 2025 ➔ Dec 2027

Trial completion date • Trial primary completion date • Atrial Fibrillation • Cardiovascular

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer (clinicaltrials.gov) - P2 | N=90 | Not yet recruiting | Sponsor: OHSU Knight Cancer Institute | Initiation date: Jan 2024 ➔ May 2024

Trial initiation date • Atrial Fibrillation • Cardiovascular • Esophageal Cancer • Gastrointestinal Cancer • Oncology

Amiodarone for the Prevention of Atrial Fibrillation After Minimally Invasive Esophagectomy in Patients With Esophageal Cancer (clinicaltrials.gov) - P2 | N=90 | Not yet recruiting | Sponsor: OHSU Knight Cancer Institute

New P2 trial • Atrial Fibrillation • Cardiovascular • Esophageal Cancer • Gastrointestinal Cancer • Oncology

Vernakalant Versus Amiodarone for Post-operative Atrial Fibrillation in Cardiac Surgery Patients (clinicaltrials.gov) - P3 | N=50 | Not yet recruiting | Sponsor: University of Calgary | Trial completion date: Sep 2024 ➔ Sep 2025 | Trial primary completion date: Jan 2024 ➔ Jan 2025

Surgery • Trial completion date • Trial primary completion date • Atrial Fibrillation • Cardiovascular

Vernakalant Versus Amiodarone for Post-operative Atrial Fibrillation in Cardiac Surgery Patients (clinicaltrials.gov) - P3 | N=50 | Not yet recruiting | Sponsor: University of Calgary | Trial completion date: Sep 2023 ➔ Sep 2024 | Trial primary completion date: Sep 2023 ➔ Jan 2024

Trial completion date • Trial primary completion date • Atrial Fibrillation • Cardiovascular

AAA: Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study (clinicaltrials.gov) - P4 | N=42 | Recruiting | Sponsor: University of Calgary | Not yet recruiting ➔ Recruiting

Enrollment open • Atrial Fibrillation • Cardiovascular

AAA: Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study (clinicaltrials.gov) - P4; N=42; Not yet recruiting; Sponsor: University of Calgary; Initiation date: Jun 2021 ➔ Sep 2021

Trial initiation date • Atrial Fibrillation • Cardiovascular

Can Statins Cause Brain Fog? (WebMD) - "'One might need to ask the question: 'Is it really the drug?' Or is there something else going on here that would require formal evaluation with a neuropsychiatric specialist,' Rosenson says."

Media quote

AAA: Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study (clinicaltrials.gov) - P4; N=42; Not yet recruiting; Sponsor: University of Calgary

New P4 trial • Atrial Fibrillation • Cardiovascular

"Read new CDC Blog: Familial Hypercholesterolemia is common 7 undertreated in the US #KnowFH #tier1 #pm101 @TheFHFoundation @nationallipid @NLAFoundation #NLASessions @NYUCVDPrevent @OHSUCardio @fhscglobal @ACCCardioEd @HeartNews @ACCinTouch @drpablocorral @gina_lundberg @Drlipid" (@lipiddoc)

Clinical • Biosimilar • Cardiovascular • Dyslipidemia

"To be fair our hospital uses the nexterone product for first dose boluses so probably ubiquitous? :)" (@CardiacRX)

Clinical

"GlaxoSmithKline @GSKUS has a number of oncology-related job openings and if you'll be at #ASHG19 in Houston this week- you can visit GSK Careers at booth 1049 #sciencejobs #oncology #genetics #genomics #PM101" (@OncologyHiring)