engineered dopamine producing neuron cell therapy / STEMCELL Technologies - LARVOL DELTA

STEMCELL Technologies Announces Successful Completion of Asset Purchase Agreement with SQZ Biotechnologies Company [Google translation] (Businesswire) - "STEMCELL Technologies is pleased to announce that it has acquired substantially all of the assets of SQZ Biotechnologies Company...This transaction, which was approved today by SQZ shareholders, marks another important milestone for STEMCELL, Canada's largest biotechnology company....Once the SQZ transaction was approved, STEMCELL was able to acquire substantially all of SQZ's assets, including its entire portfolio of more than 400 patents and trademarks, other intellectual property rights such as copyrights and trade secrets, proprietary equipment and its master license from the Massachusetts Institute of Technology."

M&A • Cervical Cancer • CNS Disorders • Gynecologic Cancers • Head and Neck Cancer • Oncology • Parkinson's Disease • Solid Tumor

SQZ Biotechnologies Announces Generation of Dopaminergic Neurons from Human Pluripotent Stem Cells Through Single-Step Delivery of Six Cell-Fate Encoding RNAs (Businesswire) - "SQZ Biotechnologies Company...presented preclinical regenerative medicine data showing that the company’s proprietary Cell Squeeze® technology can effectively generate dopaminergic (DA) neurons from human-induced pluripotent stem cells (iPSCs) through the single-step delivery of six RNA that encode for specific fate-determining transcription factors. The inclusion of non-viral, self-amplifying RNA in particular was shown to enhance and lengthen transcription factor expression and support DA neuron development. The new findings build upon the company’s recent regenerative medicine research presentations and are aligned with the company’s NIH-funded effort to generate cell replacement therapies for neurodegenerative conditions like Parkinson’s disease. The research was presented at the 2022 International Society for Stem Cell Research (ISSCR) annual meeting."

Preclinical • CNS Disorders • Parkinson's Disease