Gliora (nanoolaparib/nanotemozolomide)
/ Nanoform
- LARVOL DELTA
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November 12, 2025
A new kernel, a nanoformulated combination of olaparib (Lynparza originally developed by AstraZeneca Plc) and temozolomide (Temodar originally developed by Merck & Company Inc.), as a locally-administered, long-acting, thermo-responsive hydrogel, for the treatment of high-grade glioma, announced in partnership with Revio Therapeutics
(Nanoform Press Release)
- "Under the agreement, development costs and all licensing and commercial revenues will be shared equally between the partners, with Nanoform receiving an additional €1.5 million in accelerated revenue-share payments....Prototype development and testing is at an advanced stage, and the program is expected to be in the clinic by H2 2026. Subject to successful co-development and commercialization, GLIORA could be commercially available by 2029-30."
Launch • Licensing / partnership • Glioma
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