RXI-185 / Phio Pharma - LARVOL DELTA

Prevention of uvr induced mmp1 upregulation with mmp1 targeting self-delivering rnai (sd-rxrna) compounds may reduce the effects of skin photoaging (SID 2017) - "Solar UVA and UVB irradiation, are the causative factors for sunlight induced skin photoaging. Others have repeatedly shown, reducing the available collagenase restricts the ability of these cancer cells to effectively migrate through the Collagen 1 based ECM. The ability of RXI-185 to effect the migration rates of UVR treated fibroblasts will be further discussed."

Preclinical • Biosimilar • Melanoma • Oncology • Ophthalmology