hAb21
/ Stainwei Biotech
- LARVOL DELTA
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March 09, 2021
"I was refering to hAB21."
(@artocarpus44)
December 03, 2020
Targeting the myeloid checkpoint receptor SIRPα potentiates innate and adaptive immune responses to promote anti-tumor activity.
(PubMed, J Hematol Oncol)
- "The in vitro and in vivo antitumor activity of hAB21 broadly recapitulates that of CD47 targeted therapies despite differences in ligand expression, binding partners, and function, validating the CD47-SIRPα axis as a fundamental myeloid checkpoint pathway and its blockade as promising therapeutic intervention for treatment of human malignancies."
IO Biomarker • Journal • Immune Modulation • Inflammation • Oncology
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