R 1671 / Genmab, Roche - LARVOL DELTA

IGF2BP3 REGULATES MYC PROTEIN LEVELS IN COLORECTAL ADENOMA (DDW 2025) - " Patient-derived organoids (PDOs) were established from patient samples with the approval of the institutional ethics committee (G1035, R1671)... IGF2BP3 regulates the expression level of MYC protein that is essential for adenoma growth by promoting MYC transcription and inhibiting translation."

Colorectal Cancer • CASP3 • IGF2BP3 • MYC