BNT153
/ BioNTech
- LARVOL DELTA
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September 26, 2025
BNT152-01C: Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1 | N=86 | Completed | Sponsor: BioNTech SE | Active, not recruiting ➔ Completed
First-in-human • Trial completion • Oncology • Solid Tumor
March 21, 2025
BNT152-01C: Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1 | N=86 | Active, not recruiting | Sponsor: BioNTech SE | Recruiting ➔ Active, not recruiting | N=170 ➔ 86
Enrollment change • Enrollment closed • Oncology • Solid Tumor
July 27, 2023
Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1 | N=170 | Recruiting | Sponsor: BioNTech SE | N=112 ➔ 170 | Trial completion date: Oct 2023 ➔ Sep 2025 | Trial primary completion date: Oct 2023 ➔ Sep 2025
Enrollment change • Trial completion date • Trial primary completion date • Oncology • Solid Tumor
May 31, 2022
Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1 | N=112 | Recruiting | Sponsor: BioNTech SE | N=60 ➔ 112 | Trial completion date: Jul 2023 ➔ Oct 2023 | Trial primary completion date: Jul 2023 ➔ Oct 2023
Enrollment change • Trial completion date • Trial primary completion date • Oncology • Solid Tumor
June 18, 2021
Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1; N=60; Recruiting; Sponsor: BioNTech SE; Not yet recruiting ➔ Recruiting
Enrollment open • Oncology • Solid Tumor
March 30, 2021
BioNTech Announces Full Year 2020 Financial Results and Corporate Update
(GlobeNewswire)
- “BNT122…First patient dosing in a randomized Phase 2 trial in circulating tumor DNA positive, surgically resected Stage 2 (high risk)/Stage 3 colorectal cancer is expected in the first half of 2021…BNT152+153 – In February, the U.S. FDA approved the IND for a Phase 1 trial for BNT152+153. We plan to start a Phase 1 trial for BNT152 (encoding IL-7) plus BNT153 (encoding IL-2) in multiple solid tumors in the first half of 2021.”
New P1 trial • New P2 trial • Colorectal Cancer • Gastrointestinal Cancer • Oncology • Solid Tumor
January 14, 2021
Dose Escalation Trial of BNT152+153 in Patients With Cancer
(clinicaltrials.gov)
- P1; N=60; Not yet recruiting; Sponsor: BioNTech SE
Clinical • New P1 trial • Oncology • Solid Tumor
March 31, 2020
BioNTech announces full year 2019 financial results and corporate update
(GlobeNewswire)
- "BNT151 – Initiation of a Phase 1 trial in multiple solid tumors (optimized IL-2) is now expected in 1H 2021; BNT152+153 – Initiation of a Phase 1 trial in multiple solid tumors is now expected in 1H 2021."
New P1 trial
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