ABBV-722 / AbbVie - LARVOL DELTA

A Phase 1 Study to Assess the Effect of Itraconazole on ABBV-722 in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=12 | Active, not recruiting | Sponsor: AbbVie | Recruiting ➔ Active, not recruiting

Enrollment closed

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults. (clinicaltrials.gov) - P1 | N=12 | Completed | Sponsor: AbbVie | Active, not recruiting ➔ Completed

Trial completion

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=16 | Completed | Sponsor: AbbVie | Recruiting ➔ Completed | N=32 ➔ 16

Enrollment change • Trial completion

A Phase 1 Study to Assess the Effect of ABBV-722 on Ethinyl Estradiol and Levonorgestrel Drug Levels in Healthy Adult Female Participants (clinicaltrials.gov) - P1 | N=15 | Completed | Sponsor: AbbVie | Active, not recruiting ➔ Completed

Trial completion

A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants (clinicaltrials.gov) - P1 | N=95 | Completed | Sponsor: AbbVie | Active, not recruiting ➔ Completed

Adverse events • First-in-human • Trial completion

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults. (clinicaltrials.gov) - P1 | N=12 | Active, not recruiting | Sponsor: AbbVie | Recruiting ➔ Active, not recruiting

Enrollment closed

A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants (clinicaltrials.gov) - P1 | N=95 | Active, not recruiting | Sponsor: AbbVie | Recruiting ➔ Active, not recruiting

Adverse events • Enrollment closed • First-in-human

A Phase 1 Study to Assess the Effect of ABBV-722 on Ethinyl Estradiol and Levonorgestrel Drug Levels in Healthy Adult Female Participants (clinicaltrials.gov) - P1 | N=15 | Active, not recruiting | Sponsor: AbbVie | Recruiting ➔ Active, not recruiting

Enrollment closed

A Phase 1 Study to Assess the Effect of Itraconazole on ABBV-722 in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=12 | Recruiting | Sponsor: AbbVie

New P1 trial

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults. (clinicaltrials.gov) - P1 | N=12 | Recruiting | Sponsor: AbbVie

New P1 trial

A Phase 1 Study of a Tablet Form of ABBV-722 Taken With and Without Food in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=11 | Completed | Sponsor: AbbVie | Active, not recruiting ➔ Completed

Trial completion

A Phase 1 Study to Assess the Effect of ABBV-722 on Ethinyl Estradiol and Levonorgestrel Drug Levels in Healthy Adult Female Participants (clinicaltrials.gov) - P1 | N=16 | Recruiting | Sponsor: AbbVie

New P1 trial

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=32 | Recruiting | Sponsor: AbbVie | Not yet recruiting ➔ Recruiting

Enrollment open

A Phase 1 Study of a Tablet Form of ABBV-722 Taken With and Without Food in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=11 | Active, not recruiting | Sponsor: AbbVie | Recruiting ➔ Active, not recruiting

Enrollment closed

A Phase 1 Study of the Safety and How the Body Processes ABBV-722 and Upadacitinib After Multiple Oral Doses in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=32 | Not yet recruiting | Sponsor: AbbVie

New P1 trial

A Phase 1 Study of a Tablet Form of ABBV-722 Taken With and Without Food in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=12 | Recruiting | Sponsor: AbbVie | Not yet recruiting ➔ Recruiting

Enrollment open

A Phase 1 Study of a Tablet Form of ABBV-722 Taken With and Without Food in Healthy Adult Participants (clinicaltrials.gov) - P1 | N=12 | Not yet recruiting | Sponsor: AbbVie

New P1 trial