EB120 / Enterome, Takeda - LARVOL DELTA

Alu RNA pseudoknot alterations influence SRP9/SRP14 association. (PubMed, RNA) - "Small angle X-ray scattering followed by atomistic computation structure prediction suggests the BC200 Alu domain and its U-turn mutant both possess a canonical Alu RNA fold, while EB120 lacks one. Our results highlight the structural diversity of Alu RNA, and the impact mutations may have on Alu RNA function."

Journal • ARID1A