dosimertinib / Genuine Biotech - LARVOL DELTA

Navigating the deuteration landscape: innovations, challenges, and clinical potential of deuterioindoles. (PubMed, Chembiochem) - "This review elucidates the progression of deuterium chemistry, culminating in approval of Deutetrabenazine in 2017. This milestone has catalyzed additional research into deuterated indoles, such as Dosimertinib, which have demonstrated enhancements in stability, toxicity profiles, and therapeutic efficacy. Moreover, the review addresses challenges and patent issues in the synthesis of deuterated indoles and highlights their potential applications in precision medicine. In the future, deuterated indoles may positively impact therapy and contribute to advances in precision medicine through molecular engineering."

Journal • Targeted Protein Degradation