CardiAMP Cell Therapy (BCDA-02) / BioCardia - LARVOL DELTA

ANTICIPATED UPCOMING MILESTONES AND EVENTS (GlobeNewswire) - "BCDA-02 CardiAMP Autologous Cell Therapy in Chronic Myocardial Ischemia: CardiAMP CMI Top line Data Rollin Cohort – Q4 2025....BCDA-03 CardiALLO Allogeneic MSC Cell Therapy in Heart Failure: CardiALLO HF Nondilutive Funding – Q1 2026."

Clinical data • Financing • Cardiovascular • Heart Failure

Biocardia Phase 3 CardiAMP-HF Trial of Novel Cardiac Cell Therapy for Ischemic Heart Failure Shows Increased Survival, Decreased Cardiac Events, and Improved Quality of Life at Two Years (GlobeNewswire) - P3 | N=125 | CardiAMP-HF (NCT02438306) | Sponsor: BioCardia, Inc. | "Increased survival and reduced major adverse cardiac and cerebrovascular events (MACCE) observed study-wide, despite primary composite efficacy endpoint not reaching statistical significance....In patients with elevated NTproBNP biomarkers (50% of enrolled patients) compared to patients on optimized heart failure medication regimens alone: 13% fewer heart death equivalents (all-cause death, heart transplantation, left ventricular assist device implantation); 47% relative risk reduction in heart death equivalents....'We look forward to sharing the CardiAMP-HF two-year data with both the U.S. FDA and Japan PMDA soon to align on the pathways that could make it available for physicians and their patients as soon as possible.'"

P3 data • Cardiovascular

CardiAMP CMI: CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial (clinicaltrials.gov) - P=N/A | N=343 | Recruiting | Sponsor: BioCardia, Inc. | Trial primary completion date: Dec 2023 ➔ Jul 2025

Trial primary completion date • Cardiovascular • Myocardial Ischemia

CardiAMP CMI: CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial (clinicaltrials.gov) - P=N/A | N=343 | Recruiting | Sponsor: BioCardia, Inc. | Trial primary completion date: Dec 2022 ➔ Dec 2023

Trial primary completion date • Cardiovascular • Myocardial Ischemia

CardiAMP CMI: CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial (clinicaltrials.gov) - P=N/A; N=343; Recruiting; Sponsor: BioCardia, Inc.; Not yet recruiting ➔ Recruiting

Clinical • Enrollment open • Cardiovascular • Myocardial Ischemia

Newly added product (BioCardia Press Release) - P3, Cardiovascular

Pipeline update