Sii Somastin (somatostatin) / Serum Institute of India - LARVOL DELTA

Somatostatin Receptor Assessment and the Role of Peptide Receptor Radionuclide Therapy in Progressive Small Bowel Neuroendocrine Tumor (Targeted Oncology) - "Patient counseling is highlighted as a critical component of therapy selection. Dr Lieu describes how expected benefits, potential toxicities, and long term considerations are discussed with patients to support shared decision making. Treatment logistics, coordination across multidisciplinary teams, and monitoring strategies are also addressed."

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Somatostatin receptor PET (Ga-68 or Cu-64 DOTATATE PET) is often used for surveillance but the data supporting that practice are limited. This small study adds to that limited literature suggesting that the yield of surveillance SSTR PET is low. My take: SSTR PET is not recommended in the postoperative setting unless something suspicious is seen on cross-sectional imaging and/or there are...

Targeting VEGF Pathways in Advanced NETs: Ramucirumab Plus Somatostatin Analog Therapy (YouTube) - "Kimberly Perez, MD...provides an overview of her study that evaluated the efficacy of ramucirumab and somatostatin analog therapy in targeting VEGF pathways in patients with advanced neuroendocrine tumors. Dr. Perez goes over the rationale behind combining ramucirumab and somatostatin in the trial, how oncologists can integrate VEGF-targeting strategies into existing treatment algorithms for NETs, and the key outcomes of the study."

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Methods to achieve hemostasis in patients with acute variceal hemorrhage (UpToDate) - "Among patients with cirrhosis, varices form at a rate of 5 to 15 percent per year, and one-third of patients with varices will develop variceal hemorrhage [1]. The current treatment options for acute variceal hemorrhage include medications (vasopressin, somatostatin, and their analogs), endoscopy, transjugular intrahepatic portosystemic shunt placement, and surgery."

Online posting