ALN-F1202
/ Alnylam
- LARVOL DELTA
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September 09, 2020
Knockdown of liver-derived factor XII by GalNAc-siRNA ALN-F12 prevents thrombosis in mice without impacting hemostatic function.
(PubMed, Thromb Res)
- "Our findings support that reduction of plasma Factor XII by ALN-F12 provided thrombo-protective effects with no increased bleeding risk in rodent models of thrombosis and hemostasis."
Journal • Preclinical • Cardiovascular • Hematological Disorders • Thrombosis • Venous Thromboembolism
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