ampicillin / Generic mfg. - LARVOL DELTA

Widespread antibiotic-resistant Salmonella in reptiles and amphibians at a global exotic pet trade hub: An emerging zoonotic threat. (PubMed, One Health) - "Resistance was the highest to streptomycin (58.7%), followed by colistin (6.1%), and ampicillin (5.9%), raising critical public health concerns. This study provides evidence on MDR Salmonella in pet reptiles and amphibians, highlighting the underestimated zoonotic threats and public health risks posed by these animals in the global exotic pet trade. We advocate enhanced surveillance of resistant Salmonella in imported reptiles and amphibians and urge the enforcement of stricter regulations to mitigate pathogen transmission risks."

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Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae. (PubMed, Imeta) - "Transient ampicillin exposure creates a permissive, low-diversity intestinal niche dominated by facultative anaerobes, which supports long-term, high-density hvKp colonization...These findings provide insights into how transient antibiotic exposure could potentially drive long-term intestinal pathobiont colonization while laxative-induced osmotic perturbations do not rewire the energy and metabolic landscape of the gut microbiome, enabling rapid recovery and colonization resistance despite an initial plunge in diversity. Our work reveals that the specific mode of perturbation affects the trajectory for pathogen adaptation, and highlights the potential role of commensal competition in constraining pathogen evolution."

Journal • Infectious Disease • Pneumonia

Microbial species isolation and antimicrobial resistance patterns of burn wounds infections in a tertiary care hospital. (PubMed, Int J Burns Trauma) - "The findings provide valuable insight into the prevalence of microorganisms in burn wounds and suggest that antibiotic resistance patterns can be useful in guiding the development of effective treatment strategies."

Journal • Infectious Disease

Inter-laboratory study on analysis of veterinary medicinal product residues by liquid chromatography with triple quadrupole and/or high-resolution mass spectrometry in meat and milk matrices. (PubMed, Food Addit Contam Part A Chem Anal Control Expo Ri) - "A large-scale collaborative study, involving 32 laboratories worldwide, was conducted to evaluate the performances of low-resolution mass spectrometry (MS/MS) versus high-resolution mass spectrometry [(Q/)HRMS], both for identification and quantification of multi-class veterinary drug residues (amphenicols, cephalosporins, diaminopyrimidines, lincosamides, macrolides, penicillins, quinolones, sulfonamides, tetracyclines, avermectins, benzimidazoles, coccidiostats, NSAIDs)...A recurring source of false positives was the misidentification between ampicillin and cephalexin, especially in the case of MS/MS...Hydroxy-flunixin presented challenges in milk, especially for goat milk. Both MS/MS and (Q/)HRMS technologies were demonstrated to be useful for both qualitative and quantitative analysis, and the findings of this study underscore the importance of method optimization and careful data interpretation in multi-class veterinary drug analysis."

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Genomic epidemiology of Salmonella Typhimurium in Guizhou, China (2019-2023): high prevalence of MDR, plasmid-associated resistance, and shared genomic lineages. (PubMed, Front Microbiol) - "Substantial resistance to first-line antibiotics was also observed, including ciprofloxacin (16.5%), ceftazidime (19.4%), cefotaxime (36.9%), and azithromycin (12.6%)...Resistance genotypes correlated well with phenotypes for azithromycin, ceftazidime, ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, and tetracycline (Kappa: 0.48-0.74)...These findings highlight the cross-regional and cross-species circulation of shared genomic lineages, suggesting complex ecological networks that may involve the food supply chain. Implementing an integrated "One Health" surveillance strategy is critical to track and limit the circulation of these resistant lineages and mitigate the associated public health threat."

Journal • Gastroenterology • Gastrointestinal Disorder

Recurrent Flood Syndrome Complicated by Enterococcus Faecalis Peritonitis: Successful Conservative Management in Decompensated Cirrhosis (ACG 2026) - "Empiric ceftriaxone and metronidazole were started, then narrowed to IV ampicillin after ascitic fluid cultures grew ampicillin-sensitive E. faecalis. This case supports proactive elective surgical evaluation and TIPS reassessment once medically optimized. Figure: Figure 1 A: Spontaneous ascitic fluid drainage from an umbilical hernia (Flood syndrome) B: CT abdomen and pelvis showing a 1.6 cm rim-enhancing fluid collection adjacent to the left aspect of the supraumbilical hernia"

Cardiovascular • Fibrosis • Gastroenterology • Hepatology • Hypotension • Immunology • Infectious Disease • Portal Hypertension

Shigella Flexneri Proctocolitis Masquerading as Inflammatory Bowel Disease in a Young Adult With Newly Diagnosed HIV-1 Infection (ACG 2026) - "Post-discharge, stool culture finalized as S. flexneri resistant to ampicillin and TMP-SMX. Therapy was switched to ciprofloxacin with clinical resolution...Misclassification as LGV is well documented, as both produce proctocolitis with bleeding and rectal inflammation. This case reinforces the need for stool cultures, comprehensive STI screening, and attention to resistance patterns in MSM populations presenting with severe proctocolitis."

Clinical • Cardiovascular • Colorectal Cancer • Crohn's disease • Gastroenterology • Gastrointestinal Disorder • Heart Failure • Hepatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammation • Inflammatory Bowel Disease • CD4

Unexpected Diagnosis of Hepatocellular Carcinoma in a Young Non-Cirrhotic Patient With Listeria monocytogenes Bacteremia: A Case Report (ACG 2026) - "Empiric piperacillin-tazobactam was started. Blood cultures on day 2 grew Listeria monocytogenes, and antibiotics were narrowed to ampicillin...This case underscores the need for a high index of suspicion for hepatic malignancy in patients presenting with liver masses and systemic infection, even in young, non-cirrhotic individuals. Figure: CT abdomen showing a exophytic liver mass."

Case report • Clinical • Diabetes • Fibrosis • Hepatitis B • Hepatocellular Cancer • Hepatology • Immunology • Infectious Disease • Liver Cancer • Liver Cirrhosis • Metabolic Disorders • Oncology • Solid Tumor • Type 2 Diabetes Mellitus • MUC16

Refractory Enterococcus Faecalis Bacteremia Revealing an Occult Colonic Foreign Body in a Dual-Organ Transplant Recipient (ACG 2026) - "Despite appropriate intravenous ampicillin therapy, the patient developed persistent fevers and clinical deterioration, including headache and acute encephalopathy...This case demonstrates that refractory bacteremia in immunocompromised patients may require escalation beyond the conventional to identify atypical gastrointestinal sources. Figure: Colonoscopic visualization of a linear foreign body within the ascending colon, covered in luminal debris Figure: Colonoscopic visualization and retrieval of a linear foreign body within the ascending colon"

Clinical • CNS Disorders • Cough • Fibrosis • Hepatitis C • Hepatology • Human Immunodeficiency Virus • Immunology • Infectious Disease • Inflammation • Nephrology • Pulmonary Disease • Renal Disease • Respiratory Diseases • Septic Shock • Transplantation

Listeria Septicemia in the Setting of an Ulcerative Colitis Flare (ACG 2026) - "We present a case of Listeria septicemia in the setting of a UC flare in a patient not on biologic agent and recently started on prednisone...Blood cultures grew gram-positive bacilli, eventually speciating to Listeria monocytogenes, and antibiotics were narrowed to ampicillin. She continued mesalamine enemas twice daily, with hydrocortisone enemas added...Severe infections are more often linked to biological agents with few case reports involving corticosteroid therapy alone. [2,3]"

Acute Kidney Injury • CNS Disorders • Endocrine Disorders • Gastroenterology • Gastrointestinal Disorder • Immunology • Infectious Disease • Inflammation • Inflammatory Bowel Disease • Nephrology • Renal Disease • Septic Shock • Ulcerative Colitis

Gastric Actinomycosis Masquerading as a Gastric Ulcer: A Case Report (ACG 2026) - "The patient was treated with intravenous ampicillin followed by oral penicillin...Clinical suspicion in the right setting is paramount because Actinomyces species are highly susceptible to penicillin-based therapy, and prompt treatment may prevent unnecessary invasive procedures and improve outcomes. Figure: Fig 1: gastric ulcer occupying >70% of the gastric body Figure: H&E stain of gastric biopsy (x10) showing bacterial colonies of actinomyces, fragments of connective tissues, and detached glands"

Case report • Clinical • Cardiovascular • Chronic Obstructive Pulmonary Disease • Diabetes • Gastric Cancer • Hematological Malignancies • Immunology • Infectious Disease • Lymphoma • Metabolic Disorders • Peptic Ulcer • Respiratory Diseases • Solid Tumor • Type 2 Diabetes Mellitus

Conserved protein sequence-structure signatures identify antibiotic resistance genes from the human microbiome. (PubMed, Microbiome) - "ARG-PASS provides a precise computational approach that integrates sequence and structure to identify divergent ARGs that evade homology-based detection, supporting improved resistance surveillance and antibiotic stewardship. Video Abstract."

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Occurrence of Stenotrophomonas carrying β-lactamase-encoding genes in a veterinary hospital environment. (PubMed, Vet Res Commun) - "Antimicrobial susceptibility testing revealed a high resistance profile to ciprofloxacin, whereas resistance to tetracyclines, chloramphenicol, levofloxacin, and trimethoprim/sulfamethoxazole was less frequent. In accordance with the reported intrinsic resistance of Stenotrophomonas to a range of antibiotic classes, the strains were resistant to meropenem, ampicillin, cefoxitin, and amoxicillin/clavulanate...Together, these findings indicate that environmental Stenotrophomonas spp. strains from veterinary settings harbor multidrug resistance determinants, efflux-mediated mechanisms, and biofilm-forming capacity, highlighting their potential role in the maintenance and dissemination of clinically relevant antimicrobial resistance."

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Plastisphere as a global hotspot for antimicrobial resistance: Systematic review and quantitative synthesis. (PubMed, Mar Pollut Bull) - "Ampicillin resistance in plastisphere-associated Vibrio spp...The evidence base is geographically skewed (38% of studies from Chinese systems), and these estimates describe environmental enrichment, not realized clinical risk. They nonetheless justify incorporating polymer-additive regulation and plastisphere resistome surveillance into One Health strategies and the UN Plastics Treaty."

Journal • Review • Gene Therapies

Staphylococcus aureus contamination in traditional buffalo milk supply chain in Bangladesh. (PubMed, Trop Anim Health Prod) - "The antimicrobial resistance was found to be highest for ampicillin at 87% (n = 26), followed by penicillin at 83% (n = 25) and erythromycin at 67% (n = 20) respectively. In conclusion, the study indicates a high occurrence of resistance and biofilm-producing S. aureus along the buffalo milk supply chain. Implementing a proper supply chain and determining some critical control points are required to attain consumer safety and reduce S. aureus contamination."

Journal • Infectious Disease

Antibiotic residues and antimicrobial resistance patterns of bacteria isolated from beef at Ruti Rufura Slaughterhouse, southwestern Uganda. (PubMed, Front Microbiol) - "Among 75 viable isolates, resistance was highest to ampicillin (97.3%), chloramphenicol (86.7%), tetracycline (82.7%), ceftriaxone (57.3%), and ciprofloxacin (54.7%), while gentamicin showed the highest susceptibility (86.7%). Beef marketed in southwestern Uganda frequently contains antimicrobial residues and antimicrobial-resistant bacteria, posing a potential food safety risk. Strengthened antimicrobial stewardship, enforcement of withdrawal periods, and integrated surveillance of antimicrobial residues and resistance in foods of animal origin are needed to support One Health efforts against antimicrobial resistance."

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A Diagnostic Challenge Involving Enterococcus faecalis Bacteremia: A Case Report. (PubMed, Cureus) - "Blood cultures at 48 hours grew Gram-positive cocci in pairs and chains and Enterococcus faecalis, prompting treatment with ceftriaxone and ampicillin and an extensive search for an infectious source...Repeat blood cultures cleared, and the patient was transitioned to oral amoxicillin on discharge with outpatient follow-up. This case highlights the importance of considering gastrointestinal sources, including colorectal neoplasia, in patients with E. faecalis bacteremia of unclear origin. It also supports the role of multidisciplinary evaluation, including infectious disease, cardiology, and gastroenterology, in guiding workup and management."

Journal • Atrial Fibrillation • Cardiovascular • Colonic Polyps • Colorectal Cancer • Endocrine Disorders • Gastroenterology • Hypertension • Infectious Disease • Mood Disorders • Musculoskeletal Pain • Oncology • Pain • Pneumonia • Psychiatry • Respiratory Diseases • Solid Tumor

Prevalence, Enterotoxin Gene Profiles, Psychrotrophic Characteristics, and Antibiotic Resistance of Bacillus cereus Isolated from Ready-to-Eat Foods. (PubMed, Foodborne Pathog Dis) - "Kirby-Bauer disk diffusion testing revealed that all isolates (100%) were resistant to penicillin, with resistance also recorded for ampicillin (38.5%), tetracycline (30.8%), and clindamycin (23.1%). Collectively, these findings underscore the public health relevance of enterotoxin-carrying, cold-tolerant, and antibiotic-resistant B. cereus in RTE foods and emphasize the necessity of strengthening temperature management and sanitation measures at all stages of the food supply chain."

Journal • Gastrointestinal Disorder

Epidemiology and Antimicrobial Resistance Trends of Invasive Bacterial Pathogens in The Gambia: A Retrospective analysis, 2019-2024. (PubMed, Int J Infect Dis) - "S. aureus, E. coli, and S. pyogenes dominate IBPs at this institution in The Gambia, with some pathogens having critically high resistance to first-line antibiotics, underscoring the need for revised institution-level empirical treatment guidelines and expanded, coordinated national AMR surveillance."

Journal • Retrospective data • Infectious Disease • Pneumococcal Infections • Pneumonia

Prevalence, Serovar Diversity, and Antimicrobial Resistance Disparities ofSalmonellafrom Retail Pork and Chicken in Yuyao, China, 2019-2025. (PubMed, J Food Prot) - "Resistance was highest to ampicillin (77.2%, 348/451), tetracycline (74.9%, 338/451), and trimethoprim-sulfamethoxazole (60.5%, 273/451); all isolates were susceptible to imipenem. The ACSSuT phenotype (resistance to ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline) was detected in 14.2% (64/451) of isolates, mainly in serovar Rissen and serovar 4,[5],12:i:-, most with co-resistance to extended-spectrum cephalosporins and quinolones. Retail pork and chicken in Yuyao are highly contaminated, with high serovar diversity and severe antimicrobial resistance, underscoring the urgent need for sustained surveillance and targeted interventions."

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In vitro Biofilm-forming Ability and Antiseptic and Antimicrobial Susceptibility of Bacterial Strains Derived from Surgical-site Infections in Equine Orthopedic Surgery. (PubMed, J Equine Vet Sci) - "Biofilm formation at surgical sites should be considered following equine orthopedic surgery. In this in vitro study, povidone-iodine had greater activity than other agents against established biofilms, suggesting its potential usefulness for biofilm-associated surgical site disinfection."

Journal • Preclinical • Infectious Disease • Orthopedics

Adjuvant Antibacterial Effects of Mouriri Elliptica Against Clinical Multidrug Resistant Gram-Negative Bacterial Strains. (PubMed, Microbiologyopen) - "Synergistic interactions were observed with conventional antibiotics, particularly ciprofloxacin against K. pneumoniae, reducing MIC values up to fifteen-fold, and with ampicillin against E. coli and S. aureus...LC-MS profiling identified 41 compounds, including chlorogenic acid derivatives, flavonoids, ellagic acid derivatives, and triterpenes. Acute toxicity evaluation in mice at 2000 mg/kg revealed no adverse effects. Collectively, these findings support the potential of M. elliptica as a natural antibacterial adjuvant for enhancing the effectiveness of selected antibiotics against MDR pathogens, warranting further chemical, mechanistic, and in vivo investigation."

Journal • Infectious Disease • Pneumonia

Towards green monitoring of antibiotics: a direct biochar-based electrochemical sensor for ampicillin detection in biomedical and environmental matrices. (PubMed, Talanta) - "Because the LOQ closely matches the EU maximum residue limit (MRL) for AMP in milk, the platform enabled quantitative determination at approximately the MRL, 1.5×MRL and 2×MRL, with recoveries of 90.9%, 101.9% and 100.9%, respectively, while also supporting qualitative MRL screening in diluted samples complementary to confirmatory LC-MS/MS. AGREE (0.75) and BAGI (67.5) scores confirmed a substantially greener analytical platform than LC-MS/MS (AGREE 0.43) with practical applicability."

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Prevalence and Antibiotic Resistance Pattern of Escherichia coli Isolated from Urine Samples of Pediatric Outpatients with Underlying Medical Conditions from Pakistan. (PubMed, Infect Drug Resist) - "The highest rates of resistance were observed against ampicillin (70.3%), cephalexin (60.1%), and trimethoprim-sulfamethoxazole (59.4%). Low resistance was noted to nitrofurantoin (2.8%) and amikacin (1.8%). Age was a significant predictor, with 1-year old children showing 2.1-fold 95% CI: 1.01-4.55) and 3.6‑fold (95% CI: 1.60-8.15) increased odds of ESBL production and MDR, respectively, compared to children aged 6-12 years. High rates of ESBL-producing and MDR E. coli in Pakistani children with underlying conditions underscore the critical need for antimicrobial stewardship and empirical therapy guided by local susceptibility patterns, particularly in younger children."

Journal • Infectious Disease • Nephrology • Pediatrics

Antibiotic resistance, pathogenicity and genomic characteristics of a novel sequence type 6839 Klebsiella pneumoniae strain isolated from cultured bullfrogs (Rana catesbeiana). (PubMed, Front Cell Infect Microbiol) - "It displayed multidrug resistance against penicillins (carbenicillin, piperacillin, ampicillin, penicillin), chloramphenicol, trimethoprim and tetracycline. ZYRC75 possessed a single circular chromosome of 5,454,922 bp, carrying 179 virulence‑related genes and 157 antimicrobial‑resistance genes. This investigation presents a detailed phenotypic and genomic profile of ZYRC75, revealing its antimicrobial resistance and virulence, and establishing a basis for future studies on the pathogenicity of K. pneumoniae."

Journal • Infectious Disease • Pneumonia