BGM-2121 / BioGate Precision Medicine - LARVOL DELTA

A potent therapeutic antibody BGM-2121 targeting parathyroid hormone-related peptide (PTHrP) for pancreatic cancer (AACR 2025) - "In conclusion, this potent PTHrP-targeting antibody shows considerable promise as a therapeutic agent for cancers with PTHrP overexpression (e.g., pancreatic and lung cancers), humoral hypercalcemia of malignancy, and PTHrP-mediated cancer cachexia. We are currently preparing to submit an Investigational New Drug (IND) application to the TFDA and plan to initiate clinical trials to evaluate its potential as a novel biologic treatment for hard-to-treat metastatic cancers in Taiwan."

Colorectal Cancer • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Oral Cancer • Pancreatic Cancer • Solid Tumor • KRAS • PTHLH