PMN311 / ProMIS Neurosci - LARVOL DELTA

Data Presented at American Academy of Neurology Annual Meeting on Novel Vaccine Design for Alzheimer’s Disease (GlobeNewswire) - "ProMIS Neurosciences...presented preclinical data supporting the development of a computationally-derived amyloid-beta (Aβ) vaccine for AD at the American Academy of Neurology (AAN) 2023 Annual Meeting....The ProMIS vaccine candidate, consisting of an AβO conformational peptide epitope conjugated to KLH as a carrier protein to provide T cell help, elicited robust and sustained antibody responses with either alum or QS-21 as the adjuvants. There were no potentially deleterious T helper cell responses to the conformational AβO peptide epitope, and T helper responses developed only against the KLH carrier protein."

Preclinical • Alzheimer's Disease • CNS Disorders • Tauopathies And Synucleinopathies