gp130 modulator / CarthroniX - LARVOL DELTA

Novel Small Molecule Modulator of the gp130 Receptor Shows Dose-dependent Therapeutic Efficacy in a Canine Model of Osteoarthritis (ACR Convergence 2022) - "Taken together, these data suggest efficacy in controlling joint disease progression and its symptoms as well as a good safety profile for CX-011. We have shown that the high 10 μg and medium 1 μg dose groups prevent some of the most important pathophysiological changes promoting osteoarthritis progression. Notably, bone remodeling and shape change is prevented."

Clinical • Preclinical • Anesthesia • Immunology • Inflammation • Orthopedics • Osteoarthritis • Pain • Rheumatology • IL6